The protein family with sequence similarity 90, member A13 (FAM90A13), is a member of the FAM90A family, which belongs to a larger group of genes characterized by conserved sequences suggestive of common functional or structural properties. The FAM90A gene family's exact physiological roles are not well-characterized, but the presence of conserved motifs implies they may play a role in cellular processes that are vital across different organisms.FAM90A13, like other family members, may be involved in nuclear processes due to the presence of sequences that suggest nuclear localization. These proteins are often implicated in the regulation of gene expression, DNA repair, and replication, or chromatin remodeling due to their nuclear association. The sequence similarity across the family members suggests they share functional characteristics, possibly as part of a complex or through interactions with other proteins.
The specific function of FAM90A13 may be elucidated through studies focusing on its expression pattern, post-translational modifications, and binding partners. It is possible that FAM90A13 participates in transcriptional regulation, given its family association. In this capacity, it may act as a transcription factor itself or modulate the activity of other transcription factors or components of the transcriptional machinery.Moreover, the "90" in FAM90A13 could indicate a relationship to heat shock proteins, which are typically named for their molecular weight and are involved in protein folding and stress responses. However, without a clear functional annotation, this remains speculative for FAM90A13.
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