FAM44A Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor PD 98059 blocks the MAPK/ERK pathway. As FAM44A is implicated in cell cycle regulation, inhibition of this pathway disrupts signaling that could indirectly diminish FAM44A-mediated control of mitotic processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor LY 294002 suppresses the PI3K/Akt pathway. FAM44A, which may be involved in spindle assembly, could have its function indirectly reduced due to decreased PI3K signaling, which is critical for mitosis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor Rapamycin impedes the mTOR pathway, crucial for cell growth and proliferation. As FAM44A is associated with these cellular processes, its inhibition could indirectly lead to diminished FAM44A activity. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
CDK4/6 inhibitor PD 0332991 arrests cell cycle progression at G1, potentially impacting FAM44A's role in cell cycle regulation by diminishing its functional necessity during the cell cycle arrest. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor Y-27632 interferes with cytoskeleton dynamics by affecting actin polymerization. Since FAM44A may interact with cytoskeletal elements, its activity could be indirectly diminished by altered actin dynamics. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
TGF-β receptor inhibitor SB 431542 inhibits TGF-β signaling. If FAM44A is implicated in TGF-β related cellular processes, its inhibition through this pathway could indirectly reduce FAM44A activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
SERCA pump inhibitor Thapsigargin leads to altered calcium homeostasis. FAM44A, if modulated by calcium-dependent signaling, would have diminished activity due to disrupted calcium signaling. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor Bortezomib could indirectly decrease FAM44A activity by stabilizing proteins that negatively regulate FAM44A's function or substrates, thereby diminishing its functional role in cell cycle progression. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
Aurora A kinase inhibitor Alisertib disrupts mitotic spindle assembly, which could indirectly diminish FAM44A activity if FAM44A is involved in spindle dynamics or checkpoint regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
HDAC inhibitor Trichostatin A changes chromatin structure and gene expression. This could indirectly affect FAM44A activity by altering the expression of genes that regulate FAM44A function or stability. | ||||||