Date published: 2026-4-1

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FAM136A Activators

FAM136A activators, as found in the indirect knowledge of associated pathways or processes, are chemicals that could modulate a myriad of cellular signaling cascades. Chemicals like Forskolin and 8-Br-cAMP, which affect the cAMP levels, have the ability to influence the PKA activation. Given the broad spectrum of PKA's cellular targets, it's plausible to consider that FAM136A might be among the molecules impacted. Similarly, PMA's role in activating Protein Kinase C (PKC) sheds light on another avenue by which cellular signaling could be modified, thereby impacting FAM136A.

Furthermore, the cellular concentration of calcium, a crucial second messenger, can be modulated by chemicals like Ionomycin and A23187. Changes in calcium concentration can in turn modulate various pathways, presenting a link to FAM136A. Meanwhile, compounds like U0126, LY294002, and SB203580 serve as modulators of specific kinase-related pathways, such as ERK, PI3K-Akt, and p38 MAPK respectively. The precise interactions and regulation of kinases in a cell have far-reaching implications, making it conceivable that FAM136A, directly or indirectly, might be affected by alterations in these pathways. Lastly, Genistein's ability to influence multiple tyrosine kinase-associated pathways can further highlight the multifaceted approach to activate FAM136A.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Protein kinase C (PKC) activator. PKC activation may influence cellular signaling that intersects with potential pathways involving FAM136A.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Increases intracellular calcium levels. Elevated calcium can modulate various signaling cascades that might be associated with FAM136A activation.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$126.00
$328.00
30
(1)

A cAMP analog that can activate PKA, which in turn might influence pathways or cellular processes associated with FAM136A.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Calcium ionophore that elevates intracellular calcium levels, potentially influencing signaling cascades linked with FAM136A.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor. By modulating the PI3K-Akt pathway, it can influence various downstream targets and processes potentially associated with FAM136A.

BAPTA/AM

126150-97-8sc-202488
sc-202488A
25 mg
100 mg
$138.00
$458.00
61
(2)

Intracellular calcium chelator. Modulating calcium levels can influence signaling pathways potentially related to FAM136A activation.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

mTOR inhibitor. By influencing mTOR signaling, it might play a role in cellular processes associated with FAM136A.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$260.00
$350.00
$500.00
34
(1)

PDE inhibitor that increases cAMP levels, which can indirectly activate pathways or processes potentially linked with FAM136A.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

p38 MAPK inhibitor. The modulation of p38 MAPK signaling might have indirect effects on FAM136A's activity.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Broad-spectrum tyrosine kinase inhibitor. This can influence multiple signaling pathways, some of which might be associated with FAM136A.