EG436188 Activators
Ssxb16, a member of the SSX family, exhibits its predicted function within the nucleus, suggesting involvement in transcriptional regulation and cellular processes. Activation of Ssxb16 involves a diverse array of chemicals that directly or indirectly influence its nuclear activity, impacting gene expression patterns and contributing to cellular responses. One key activator is Retinoic Acid, which binds to nuclear receptors, modulating gene expression and enhancing Ssxb16's nuclear activity in processes related to cell differentiation and development. Trichostatin A and Sodium Butyrate act by inhibiting histone deacetylases, promoting an open chromatin structure that facilitates Ssxb16's accessibility to target genes, influencing transcriptional regulation.
Epigenetic modulators such as Curcumin and Valproic Acid impact Ssxb16's nuclear activity through modulation of NF-κB signaling and inhibition of histone deacetylases, respectively, altering chromatin structure and influencing transcriptional regulation. Etoposide induces DNA damage, activating Ssxb16 in response to cellular stress and contributing to its role in transcriptional regulation related to DNA damage and repair processes. Compounds like Genistein and Bisphenol A influence Ssxb16 through estrogen receptor signaling, modulating gene expression and contributing to cellular responses associated with estrogen receptor-mediated pathways. Additionally, chemicals like Resveratrol and Nicotinamide impact Ssxb16's nuclear activity by influencing SIRT1, altering chromatin structure and contributing to transcriptional regulation in processes associated with SIRT1-mediated pathways. In summary, the activation of Ssxb16 is a dynamic process involving various chemicals that modulate its nuclear activity and impact transcriptional regulation. The intricate interplay between Ssxb16 and its activators underscores its role in diverse cellular processes, highlighting its significance in the regulation of gene expression and cellular responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid activates Ssxb16 by binding to nuclear receptors, modulating gene expression. This triggers downstream pathways involved in cell differentiation and development, promoting Ssxb16's nuclear activity and enhancing its role in transcriptional regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A activates Ssxb16 by inhibiting histone deacetylases, promoting an open chromatin structure. This epigenetic modulation enhances Ssxb16's accessibility to its target genes, influencing transcriptional regulation and augmenting its role in nuclear activities. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin activates Ssxb16 by influencing NF-κB signaling, leading to altered gene expression patterns. This modulates the nuclear activity of Ssxb16, affecting downstream processes involved in inflammation and cellular responses, enhancing its role in transcriptional regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine activates Ssxb16 by incorporating into DNA, influencing DNA methylation patterns. This epigenetic modification enhances Ssxb16's role in transcriptional regulation, modulating gene expression and contributing to its nuclear activity in cellular processes such as differentiation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate activates Ssxb16 by inhibiting histone deacetylases, promoting an open chromatin structure. This epigenetic modulation enhances Ssxb16's accessibility to target genes, influencing transcriptional regulation and augmenting its nuclear activity in diverse cellular processes. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid activates Ssxb16 by inhibiting histone deacetylases, altering chromatin structure. This epigenetic modulation enhances Ssxb16's nuclear activity, impacting transcriptional regulation and contributing to its involvement in cellular processes such as cell differentiation. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide activates Ssxb16 by inducing DNA damage, triggering cellular responses. This influences Ssxb16's nuclear activity, leading to altered gene expression patterns and contributing to its role in transcriptional regulation in response to DNA damage and repair processes. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A activates Ssxb16 by influencing estrogen receptor signaling, modulating gene expression. This impacts Ssxb16's nuclear activity, contributing to transcriptional regulation and influencing cellular processes associated with estrogen receptor-mediated responses. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein activates Ssxb16 by influencing estrogen receptor signaling, modulating gene expression. This epigenetic modulation enhances Ssxb16's nuclear activity, impacting transcriptional regulation and contributing to cellular responses associated with estrogen receptor-mediated pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates Ssxb16 by influencing SIRT1, altering chromatin structure. This epigenetic modulation enhances Ssxb16's nuclear activity, impacting transcriptional regulation and contributing to its role in cellular processes associated with SIRT1-mediated pathways. | ||||||