Date published: 2025-12-19

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DYX1C1 Inhibitors

DYX1C1 inhibitors are a class of chemical compounds designed to specifically target and inhibit the function of the DYX1C1 protein, which is associated with various cellular processes, particularly those related to cellular organization and gene regulation. DYX1C1, also known as Dyslexia Susceptibility 1 Candidate 1, has been studied for its potential role in brain development and ciliary function, where it is thought to contribute to the proper functioning of the cilia, the hair-like structures on the surface of cells that play a key role in signaling and cellular movement. The protein is also involved in the regulation of gene expression, particularly in the context of neuronal development, where it may influence the formation and maintenance of neural circuits. The mechanism by which DYX1C1 inhibitors function typically involves binding to functional domains of the DYX1C1 protein, such as regions responsible for its interaction with other proteins or its involvement in regulating gene transcription. This binding prevents DYX1C1 from performing its normal functions, leading to disruptions in the cellular processes it regulates. Inhibiting DYX1C1 can interfere with the maintenance of ciliary structure and function, potentially affecting processes like cell signaling, movement, and sensory reception. Additionally, the inhibition of DYX1C1 might impact its role in the regulation of gene expression, particularly genes that are critical for neuronal development and function. By studying the effects of DYX1C1 inhibition, researchers can gain valuable insights into the specific roles this protein plays in cellular physiology, contributing to a deeper understanding of the molecular mechanisms that underlie cellular organization, neural development, and the maintenance of proper cellular function. This knowledge is essential for unraveling the complex interactions between proteins and signaling pathways that sustain cellular health and development.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A may lead to hyperacetylation of histones associated with the DYX1C1 gene promoter, resulting in a more open chromatin state that could decrease transcription of the DYX1C1 gene.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine could inhibit DNA methylation at the DYX1C1 gene locus, potentially leading to a reduction in gene silencing and a subsequent decrease in DYX1C1 expression.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic acid may induce hyperacetylation of histones near the DYX1C1 gene, which could hinder the recruitment of transcriptional repressors, resulting in a lowered expression of DYX1C1.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium butyrate, as a histone deacetylase inhibitor, could promote an open chromatin configuration at the DYX1C1 locus, which could lead to a suppressed transcriptional activity of the DYX1C1 gene.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Suberoylanilide Hydroxamic Acid may cause increased acetylation of histones at the DYX1C1 promoter, potentially disrupting the initiation of transcription and leading to decreased levels of DYX1C1 mRNA.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A has the potential to bind DNA at the DYX1C1 gene promoter, obstructing transcription factor access and thus downregulating DYX1C1 gene transcription.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D may intercalate into DNA of the DYX1C1 gene, blocking RNA polymerase movement and leading to a reduction in the transcription of the DYX1C1 gene.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin could inhibit the mTOR pathway, which may lead to reduced protein synthesis and could have downstream effects that result in the inhibition of DYX1C1 gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

5-Aza-2′-Deoxycytidine may decrease DNA methylation levels at the DYX1C1 gene, which could lead to a reduction in the expression of the DYX1C1 gene by altering epigenetic marks that control gene silencing.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$76.00
$255.00
18
(1)

Hydroxyurea can disrupt the DNA replication machinery, and this disruption could extend to a decrease in the transcriptional activity of genes such as DYX1C1.