Dynactin 6 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting its polymerization into microtubules, leading to disruption of microtubule-dependent processes. This inhibition potentially affects Dynactin 6 function by impairing cargo transport mechanisms. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole interferes with microtubule polymerization, causing microtubule depolymerization. This action can indirectly inhibit Dynactin 6 by disrupting its role in dynein-mediated cargo transport along microtubules. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Taxol stabilizes microtubules, preventing their depolymerization. This paradoxical action may indirectly affect Dynactin 6 activity by altering normal microtubule dynamics and, consequently, dynein-driven transport processes. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin, preventing microtubule assembly. This disruption of microtubule formation can indirectly affect Dynactin 6 by impairing microtubule-dependent cellular transport and signaling pathways. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits the growth phase of microtubules without affecting their shortening, leading to abnormal mitotic spindles. This mechanism indirectly impacts Dynactin 6 by disrupting microtubule-dependent processes. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits tubulin polymerization, leading to microtubule destabilization. This effect can indirectly inhibit Dynactin 6 function by disrupting microtubule-dependent transport and signaling. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D disrupts actin filament organization, which can indirectly affect Dynactin 6 by altering cellular transport mechanisms that rely on the cytoskeleton, including those dependent on microtubules. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A binds to actin monomers, preventing their polymerization. This disruption of actin filaments can indirectly influence Dynactin 6 function by affecting cytoskeletal dynamics and associated transport processes. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to tubulin, potentially affecting Dynactin 6 by impairing microtubule-dependent cellular processes, including intracellular transport. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate, primarily known for its action in inhibiting dihydrofolate reductase, can indirectly affect cellular signaling pathways and, consequently, processes involving Dynactin 6 through its broader cytotoxic effects. | ||||||