Date published: 2025-10-24

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DOHH Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DOHH monoclonal antibodies for advanced research in molecular biology. DOHH monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Dihydrouridine synthase (DOHH) plays a critical role in the post-transcriptional modification of tRNA, specifically in the conversion of uridine to dihydrouridine. This modification is essential for the proper folding and function of tRNA, which in turn is crucial for accurate protein synthesis. Understanding DOHH function is important for elucidating the mechanisms of gene expression and regulation, as well as its implications in various diseases. Research has shown that DOHH activity is particularly significant in cellular development and differentiation. Investigating DOHH can provide insights into fundamental biological processes and potential therapeutic targets. Recent studies have highlighted the importance of DOHH in maintaining cellular homeostasis and its potential role in disease progression. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of DOHH and contribute to breakthrough discoveries in molecular biology.

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DOHH Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DOHH Antibody (B-12)

sc-376929mouse IgG2a κ271-299 (h)WB, IP, IF, IHC(P), ELISAh
3
(2)

DOHH Antibody (E-2)

sc-271868mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
2
(2)

DOHH CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DOHH CRISPR/Cas9 KO Plasmid (h)

sc-404524hGene KnockoutGFP0
(0)

DOHH HDR Plasmid (h)

sc-404524-HDRhHomology Directed RepairPuromycin0
(0)

DOHH Double Nickase Plasmid (h)

sc-404524-NIChGene KnockoutPuromycin0
(0)

DOHH Double Nickase Plasmid (h2)

sc-404524-NIC-2hGene KnockoutPuromycin0
(0)

DOHH CRISPR/Cas9 KO Plasmid (m)

sc-430410mGene KnockoutGFP0
(0)

DOHH HDR Plasmid (m)

sc-430410-HDRmHomology Directed RepairPuromycin0
(0)

DOHH Double Nickase Plasmid (m)

sc-430410-NICmGene KnockoutPuromycin0
(0)

DOHH Double Nickase Plasmid (m2)

sc-430410-NIC-2mGene KnockoutPuromycin0
(0)

DOHH CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DOHH CRISPR Activation Plasmid (h)

sc-404524-ACThGene ActivationPuro, Blast, Hygro0
(0)

DOHH CRISPR Activation Plasmid (h2)

sc-404524-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

DOHH Lentiviral Activation Particles (h)

sc-404524-LAChGene ActivationPuro, Blast, Hygro0
(0)

DOHH Lentiviral Activation Particles (h2)

sc-404524-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

DOHH CRISPR Activation Plasmid (m)

sc-430410-ACTmGene ActivationPuro, Blast, Hygro0
(0)

DOHH CRISPR Activation Plasmid (m2)

sc-430410-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

DOHH Lentiviral Activation Particles (m)

sc-430410-LACmGene ActivationPuro, Blast, Hygro0
(0)

DOHH Lentiviral Activation Particles (m2)

sc-430410-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

DOHH siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DOHH siRNA (h)

sc-62222hGene SilencingN/A0
(0)

DOHH shRNA Plasmid (h)

sc-62222-SHhGene SilencingPuromycin0
(0)

DOHH shRNA (h) Lentiviral Particles

sc-62222-VhGene SilencingPuromycin0
(0)

DOHH siRNA (m)

sc-62223mGene SilencingN/A0
(0)

DOHH shRNA Plasmid (m)

sc-62223-SHmGene SilencingPuromycin0
(0)

DOHH shRNA (m) Lentiviral Particles

sc-62223-VmGene SilencingPuromycin0
(0)