Date published: 2025-10-3

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Diva Activators

Diva activators represent a class of chemical compounds designed to modulate the activity of Diva, an acronym for DNA-Binding Diva (Diva) protein. The Diva protein, also known as CIDEA (Cell Death-Inducing DFFA-Like Effector A), belongs to a family of proteins known as cell death-inducing DFFA-like effector (CIDE) proteins. These proteins are involved in various cellular processes, including lipid metabolism, apoptosis, and cell death regulation. Diva, specifically, has garnered significant attention for its role in lipid droplet dynamics and adipose tissue metabolism, making it a key player in metabolic pathways.

Diva activators are meticulously engineered to interact with Diva and influence its cellular functions. By targeting Diva, these compounds may modulate its involvement in lipid metabolism and its interactions with other proteins or molecules within cells. Research on Diva activators offers valuable insights into the intricate mechanisms governing lipid storage and utilization in adipose tissue and other cell types. Understanding the molecular basis of Diva activation is essential for unraveling the complexities of metabolic regulation and its implications for overall health and metabolic diseases. Further investigation is needed to elucidate the precise mechanisms of action and biological consequences associated with Diva activation, providing a deeper understanding of cellular physiology and the regulation of lipid metabolism.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Etoposide induces DNA damage, which can activate apoptotic pathways and potentially upregulate Diva/BAD expression as part of the cellular response.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent kinase inhibitor that induces apoptosis, possibly leading to increased Diva/BAD expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Camptothecin inhibits DNA replication enzymes, causing DNA damage and possibly upregulating Diva/BAD in response.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$30.00
$60.00
$93.00
27
(1)

Hydrogen peroxide generates oxidative stress, which can induce apoptosis and Diva/BAD expression.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

Thapsigargin induces endoplasmic reticulum stress, which may lead to the upregulation of pro-apoptotic proteins like Diva/BAD.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits protein synthesis, inducing stress responses that could elevate Diva/BAD expression.

Sodium (meta)arsenite

7784-46-5sc-250986
sc-250986A
100 g
1 kg
$106.00
$765.00
3
(2)

Sodium arsenite causes cellular stress and may enhance Diva/BAD expression as a result.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone is a glucocorticoid that can induce apoptosis in certain cells, potentially affecting Diva/BAD levels.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$56.00
$260.00
$416.00
129
(3)

Sorafenib is a kinase inhibitor that may lead to apoptosis and an increase in Diva/BAD expression in certain cancer cells.

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$56.00
$212.00
$764.00
24
(1)

Nutlin-3 disrupts p53-MDM2 interaction, potentially enhancing apoptosis and Diva/BAD expression.