DHRS7 Activators

DHRS7, or Dehydrogenase/Reductase 7, is a member of the short-chain dehydrogenase/reductase (SDR) superfamily of enzymes. This enzyme is encoded by the DHRS7 gene in humans. The SDR family includes a wide range of enzymes that are involved in the metabolism of various biological molecules, including steroids, lipids, carbohydrates, and xenobiotics. They are characterized by their ability to catalyze oxidation-reduction (redox) reactions, where they either reduce or oxidize their substrates.

DHRS7 specifically exhibits oxidoreductase activity, playing a role in the metabolism of certain lipid-soluble molecules. This activity is crucial for the proper functioning of various metabolic pathways in the body. While the precise biological function of DHRS7 is not fully understood, it is known to be involved in the metabolism of steroids and retinoids. Retinoids, derivatives of vitamin A, are vital for vision, growth, cell division, reproduction, and immunity.The DHRS7 enzyme is widely expressed in human tissues, including the liver, kidneys, heart, and brain, indicating its importance in general physiology. Research suggests that DHRS7 may have a role in the pathophysiology of certain diseases, such as metabolic disorders, although the specifics of these associations are still being investigated.