Date published: 2025-10-18

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 71 to 80 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-(3-Methylbutyryl)-5,5-dimethyl-1,3-cyclohexandione

172611-72-2sc-237857
5 ml
$167.00
(0)

2-(3-Methylbutyryl)-5,5-dimethyl-1,3-cyclohexandione acts as a versatile derivatization agent, notable for its ability to form stable adducts through electrophilic interactions. The presence of the diketone structure facilitates enolization, enhancing reactivity with nucleophiles. Its bulky cyclohexandione framework imparts steric effects that can modulate reaction pathways, leading to selective derivatization. This compound's unique spatial arrangement contributes to its effectiveness in analytical applications.

9-Fluorenylmethyl N-hydroxycarbamate

190656-01-0sc-239139
5 g
$156.00
(0)

9-Fluorenylmethyl N-hydroxycarbamate serves as a powerful derivatization agent, characterized by its ability to form stable carbamate linkages through nucleophilic attack. The presence of the fluorenyl group enhances the compound's lipophilicity, promoting selective interactions with various analytes. Its unique structure allows for efficient protection of amines, while the N-hydroxy functionality facilitates rapid reaction kinetics, making it ideal for complex sample preparation in analytical chemistry.

4-(7-Diethylaminocoumarin-3-yl)benzoyl cyanide

203256-20-6sc-226395
5 mg
$122.00
(0)

4-(7-Diethylaminocoumarin-3-yl)benzoyl cyanide acts as a versatile derivatization agent, notable for its ability to form robust cyanohydrin derivatives through electrophilic attack. The diethylaminocoumarin moiety imparts strong fluorescence, enabling sensitive detection of target molecules. Its unique reactivity profile allows for selective modifications of functional groups, while the cyanide functionality enhances nucleophilic reactivity, facilitating efficient derivatization in various analytical applications.

4-(1-Methylhydrazino)-7-nitrobenzofurazan

214147-22-5sc-252076
50 mg
$263.00
(0)

4-(1-Methylhydrazino)-7-nitrobenzofurazan serves as a potent derivatization agent, characterized by its ability to engage in nucleophilic substitution reactions. The nitrobenzofurazan structure enhances electron affinity, promoting rapid reaction kinetics with electrophiles. Its unique hydrazino group facilitates the formation of stable adducts, allowing for selective tagging of analytes. This compound's distinct photophysical properties also enable effective monitoring of reaction progress in analytical settings.

1-(Benzyloxycarbonyl)benzotriazole

57710-80-2sc-311568
sc-311568A
5 g
25 g
$200.00
$400.00
(0)

1-(Benzyloxycarbonyl)benzotriazole serves as a potent derivatization agent, characterized by its ability to form stable acyl derivatives through acylation reactions. The benzotriazole moiety enhances reactivity towards nucleophiles, promoting selective modifications. Its unique structure allows for effective stabilization of reaction intermediates, facilitating smoother reaction kinetics. Additionally, the benzyloxycarbonyl group contributes to improved solubility, making it suitable for diverse organic transformations.

Allylbromodimethylsilane

302911-93-9sc-233838
5 ml
$200.00
(0)

Allylbromodimethylsilane serves as a potent derivatization agent, characterized by its ability to engage in electrophilic reactions due to the presence of the bromine atom. This compound exhibits a unique reactivity profile, enabling selective alkylation of nucleophiles. The allyl group enhances the formation of carbon-carbon bonds, while the dimethylsilane moiety contributes to increased stability and compatibility with various reaction environments. Its distinctive properties facilitate the modification of diverse substrates, streamlining synthetic pathways.

2-Benzyloxy-1-methylpyridinium triflate

882980-43-0sc-251700
1 g
$131.00
(0)

2-Benzyloxy-1-methylpyridinium triflate is a versatile derivatization agent known for its strong electrophilic character, attributed to the triflate group. This compound promotes rapid and selective reactions with nucleophiles, enhancing the formation of stable intermediates. Its unique benzyloxy substituent aids in solubility and reactivity, allowing for efficient functionalization of various substrates. The compound's ability to facilitate complex synthetic transformations makes it a valuable tool in organic chemistry.

Allyltrichlorosilane

107-37-9sc-239211
5 g
$56.00
(0)

Allyltrichlorosilane acts as a versatile derivatization agent, notable for its ability to introduce silicon functionalities into organic molecules. Its chlorosilane groups readily engage in nucleophilic substitution reactions, enabling the formation of siloxane bonds. The presence of the allyl group enhances reactivity, allowing for selective coupling with various substrates. This compound's unique reactivity profile facilitates the creation of complex silane derivatives, expanding the scope of synthetic applications.

Malonamide

108-13-4sc-215284
100 g
$56.00
(0)

Malonamide serves as an effective derivatization agent, characterized by its ability to form stable amide linkages through nucleophilic attack on electrophilic centers. Its dual functional groups enable selective interactions with a variety of substrates, promoting efficient reaction pathways. The compound's unique hydrogen bonding capabilities enhance solubility and reactivity, facilitating the formation of diverse derivatives. This versatility makes malonamide a valuable tool in synthetic chemistry for modifying organic compounds.

Trifluoromethanesulfonyl chloride

421-83-0sc-253756
5 g
$79.00
(0)

Trifluoromethanesulfonyl chloride is a potent derivatization agent known for its reactivity as an acid halide. It readily engages in nucleophilic acyl substitution, allowing for the formation of sulfonamide linkages. The presence of trifluoromethyl groups enhances electrophilicity, promoting rapid reaction kinetics with nucleophiles. Its strong electron-withdrawing properties facilitate selective derivatization, making it an effective choice for modifying various functional groups in organic synthesis.