Date published: 2025-10-19

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 131 to 140 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ethoxytrichlorosilane

1825-82-7sc-227998
25 ml
$213.00
(0)

Ethoxytrichlorosilane acts as a versatile derivatization agent, characterized by its ability to form siloxane bonds through nucleophilic substitution. The presence of three reactive chlorine atoms facilitates rapid reaction with alcohols and amines, leading to the formation of silane derivatives. Its unique reactivity profile allows for the modification of surfaces and the creation of silane networks, enhancing adhesion and stability in various applications. The compound's hydrophobic nature further influences its interaction with polar substrates, promoting selective derivatization pathways.

Benzylchlorodimethylsilane

1833-31-4sc-227340
sc-227340A
5 ml
1 L
$103.00
$13260.00
(0)

Benzylchlorodimethylsilane serves as an effective derivatization agent, notable for its ability to introduce benzyl and dimethyl groups into various substrates. Its reactivity stems from the presence of a chlorine atom, which readily engages in nucleophilic attack, enabling the formation of stable silane linkages. This compound exhibits unique steric effects due to its bulky benzyl group, influencing reaction kinetics and selectivity. Additionally, its hydrophobic characteristics enhance compatibility with non-polar environments, facilitating targeted modifications.

1-Chloro-1-methylsilacyclobutane

2351-34-0sc-251495
5 g
$260.00
(0)

1-Chloro-1-methylsilacyclobutane is a versatile derivatization agent characterized by its unique silacyclobutane structure, which promotes ring strain and enhances reactivity. The chlorine atom facilitates nucleophilic substitution, allowing for efficient functionalization of various substrates. Its distinct molecular geometry contributes to selective interactions, while the presence of the methyl group influences steric hindrance, optimizing reaction pathways. This compound's unique properties enable tailored modifications in diverse chemical environments.

1,3-Dichloro-1,1,3,3-tetramethyldisiloxane

2401-73-2sc-229818
25 ml
$183.00
(0)

1,3-Dichloro-1,1,3,3-tetramethyldisiloxane serves as a powerful derivatization agent, distinguished by its siloxane backbone that imparts flexibility and enhances molecular interactions. The presence of two chlorine atoms facilitates electrophilic attack, promoting rapid reaction kinetics with nucleophiles. Its unique structure allows for selective functionalization, while the bulky methyl groups provide steric protection, enabling precise modifications in complex chemical systems.

1,2-Bis(trichlorosilyl)ethane

2504-64-5sc-237662
sc-237662A
1 g
5 g
$34.00
$110.00
1
(0)

1,2-Bis(trichlorosilyl)ethane is a versatile derivatization agent characterized by its dual trichlorosilyl groups, which enhance reactivity through strong electrophilic character. This compound exhibits unique molecular interactions, allowing for efficient silanization of various substrates. Its ability to form stable siloxane linkages facilitates the creation of robust networks, while the steric hindrance from the trichlorosilyl moieties ensures selective targeting in complex chemical environments.

Tetrabutylammonium p-Nitrophenoxide

3002-48-0sc-296488
sc-296488A
5 g
25 g
$79.00
$196.00
(0)

Tetrabutylammonium p-Nitrophenoxide serves as a potent derivatization agent, distinguished by its quaternary ammonium structure that enhances solubility and reactivity in organic solvents. The nitrophenoxide moiety introduces strong electron-withdrawing effects, promoting nucleophilic attack in various reactions. Its unique ability to stabilize intermediates through hydrogen bonding and π-π interactions allows for selective derivatization, optimizing reaction kinetics and product yields in complex mixtures.

Chloro(dimethyl)isopropylsilane

3634-56-8sc-239507
25 g
$190.00
(0)

Chloro(dimethyl)isopropylsilane acts as a versatile derivatization agent, characterized by its silane functionality that facilitates robust covalent bonding with nucleophiles. The presence of chlorine enhances electrophilicity, promoting rapid reaction rates. Its unique steric hindrance from the isopropyl group allows for selective targeting of functional groups, while the dimethyl substituents contribute to increased stability and solubility in non-polar environments, making it effective in complex chemical transformations.

Trichlorododecylsilane

4484-72-4sc-251309A
sc-251309
25 ml
100 ml
$51.00
$120.00
(0)

Trichlorododecylsilane serves as a potent derivatization agent, distinguished by its long hydrophobic dodecyl chain that enhances lipophilicity and facilitates interactions with non-polar substrates. The three chlorine atoms confer significant electrophilic character, enabling swift reactions with nucleophiles. Its unique structure promotes selective functionalization, while the silane moiety ensures strong covalent linkages, making it ideal for modifying surfaces and enhancing material properties in various chemical processes.

Dichloro(methyl)propylsilane

4518-94-9sc-234582
25 ml
$198.00
(0)

Dichloro(methyl)propylsilane acts as an effective derivatization agent, characterized by its dual chlorine substituents that enhance reactivity towards nucleophiles. The presence of a methyl group introduces steric effects, influencing reaction kinetics and selectivity. Its silane backbone allows for robust covalent bonding, facilitating the formation of stable derivatives. This compound's unique molecular architecture enables tailored modifications, optimizing interactions in diverse chemical environments.

Chloro[2-(3-cyclohexen-1-yl)ethyl]dimethylsilane

5089-25-8sc-234321
25 ml
$242.00
(0)

Chloro[2-(3-cyclohexen-1-yl)ethyl]dimethylsilane serves as a versatile derivatization agent, distinguished by its cyclohexene moiety that promotes unique steric and electronic interactions. The dimethylsilane group enhances hydrophobicity, influencing solubility and reactivity in various solvents. Its ability to form stable siloxane bonds allows for selective functionalization, while the cyclohexenyl structure can engage in ring-opening reactions, broadening its utility in complex chemical transformations.