Date published: 2025-9-14

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 121 to 130 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chlorotributylsilane

995-45-9sc-239536
sc-239536A
5 g
25 g
$84.00
$309.00
(0)

Chlorotributylsilane is a powerful derivatization agent characterized by its ability to create robust silyl derivatives through its chlorosilane group. This compound exhibits unique reactivity with alcohols and amines, leading to the formation of silyl ethers that enhance the analytes' thermal stability and volatility. Its bulky butyl groups provide significant steric protection, allowing for selective derivatization and improved resolution in complex sample matrices, making it a valuable asset in analytical chemistry.

1,4-Phenylenebis(chlorodimethylsilane)

1078-97-3sc-224950
5 g
$99.00
(0)

1,4-Phenylenebis(chlorodimethylsilane) serves as an effective derivatization agent, notable for its dual chlorodimethylsilane functionalities that facilitate selective silylation. This compound engages in rapid reactions with nucleophiles, enhancing the stability and detectability of target analytes. Its unique structure promotes efficient steric hindrance, allowing for tailored interactions in complex mixtures, thereby improving analytical resolution and specificity in various applications.

Bromotriethylsilane

1112-48-7sc-227534
5 g
$245.00
(0)

Bromotriethylsilane is a versatile derivatization agent characterized by its bromine substituent, which enhances electrophilic reactivity. This compound readily engages in nucleophilic substitution reactions, facilitating the formation of stable silyl ethers. Its triethylsilane moiety provides significant steric bulk, promoting selective derivatization in complex matrices. The compound's unique reactivity profile allows for efficient modification of functional groups, improving the sensitivity and resolution in analytical techniques.

Dichloro(3-cyanopropyl)methylsilane

1190-16-5sc-227798
5 ml
$36.00
(0)

Dichloro(3-cyanopropyl)methylsilane serves as a potent derivatization agent, distinguished by its dual chlorine substituents that enhance its electrophilic character. This compound exhibits a unique ability to form stable siloxane bonds through nucleophilic attack, enabling selective modification of various functional groups. Its 3-cyanopropyl group introduces polar characteristics, facilitating interactions with diverse analytes and improving chromatographic performance. The compound's reactivity is further influenced by its steric and electronic properties, allowing for tailored derivatization strategies in complex analytical scenarios.

Dichloro(chloromethyl)methylsilane

1558-33-4sc-252692
sc-252692A
sc-252692B
25 g
100 g
250 g
$70.00
$194.00
$485.00
(0)

Dichloro(chloromethyl)methylsilane is a versatile derivatization agent characterized by its unique chloromethyl and dichloro substituents, which enhance its reactivity towards nucleophiles. This compound facilitates the formation of silane derivatives through efficient electrophilic substitution, promoting selective functionalization of target molecules. Its ability to engage in diverse reaction pathways allows for the fine-tuning of chemical properties, making it suitable for complex analytical applications. The presence of multiple halogen atoms contributes to its distinctive interaction dynamics, enabling enhanced stability and specificity in derivatization processes.

Chloro(methyl)phenylsilane

1631-82-9sc-227604
5 ml
$428.00
(0)

Chloro(methyl)phenylsilane serves as a potent derivatization agent, distinguished by its phenyl and chloromethyl groups that enhance its electrophilic character. This compound exhibits rapid reaction kinetics with nucleophiles, facilitating the formation of siloxane bonds and enabling selective modifications of organic substrates. Its unique molecular structure promotes diverse interaction pathways, allowing for tailored chemical transformations and improved specificity in analytical methodologies. The presence of the phenyl group further contributes to its stability and reactivity, making it an effective tool in various chemical applications.

Chlorodiphenylsilane

1631-83-0sc-227622
5 ml
$86.00
(0)

Chlorodiphenylsilane is a versatile derivatization agent characterized by its dual phenyl substituents, which enhance its steric and electronic properties. This compound exhibits a strong tendency to engage in nucleophilic substitution reactions, leading to the formation of stable siloxane linkages. Its unique structure allows for selective targeting of functional groups, promoting efficient derivatization processes. Additionally, the compound's hydrophobic nature aids in the solubilization of organic substrates, enhancing reaction efficiency and specificity in various chemical transformations.

Dichlorophenylsilane

1631-84-1sc-234602
10 g
$100.00
(0)

Dichlorophenylsilane serves as a potent derivatization agent, distinguished by its chlorinated silane structure that facilitates robust electrophilic interactions. The presence of two chlorine atoms enhances its reactivity, allowing for rapid formation of siloxane bonds through nucleophilic attack. This compound's unique ability to selectively modify functional groups is complemented by its hydrophobic characteristics, which improve the solubility of organic compounds and optimize reaction kinetics in diverse chemical environments.

3-Methyl-1-phenyl-4-trifluoroacetyl-2-pyrazolin-5-one

1691-93-6sc-226130
5 g
$374.00
(0)

3-Methyl-1-phenyl-4-trifluoroacetyl-2-pyrazolin-5-one is a versatile derivatization agent characterized by its trifluoroacetyl moiety, which enhances electrophilicity and promotes selective acylation of nucleophiles. Its unique pyrazolone framework allows for specific interactions with various functional groups, facilitating efficient reaction pathways. The compound's strong electron-withdrawing trifluoromethyl groups contribute to its stability and reactivity, making it effective in modifying complex organic substrates.

2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione

1755-15-3sc-237895
1 g
$165.00
(0)

2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione serves as a potent derivatization agent, notable for its diketone structure that enables selective reactivity with nucleophiles. The compound's unique cyclohexanedione framework enhances its ability to form stable adducts through intramolecular hydrogen bonding, promoting efficient reaction kinetics. Its sterically hindered environment allows for tailored interactions with various substrates, making it a valuable tool in organic synthesis.