Date published: 2025-9-12

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 111 to 120 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chloro(methyl)diphenylsilane

144-79-6sc-239509
25 g
$100.00
(0)

Chloro(methyl)diphenylsilane is a highly reactive derivatization agent characterized by its unique ability to form stable siloxane linkages through nucleophilic attack. The presence of both chloromethyl and diphenyl groups enhances its electrophilicity, promoting selective reactions with various nucleophiles. This compound exhibits distinct pathways for cross-linking and polymerization, contributing to the development of complex silane networks. Its hydrophobic nature also aids in modifying surface properties, making it significant in advanced material formulations.

Dichloro(methyl)phenylsilane

149-74-6sc-227801
100 ml
$123.00
(0)

Dichloro(methyl)phenylsilane serves as a potent derivatization agent, distinguished by its dual reactivity profile. The chlorinated sites facilitate rapid electrophilic substitution, allowing for efficient functionalization of nucleophiles. Its unique structure promotes the formation of robust silane bonds, enhancing compatibility with diverse substrates. Additionally, the compound's steric properties influence reaction kinetics, enabling tailored modifications in polymer chemistry and surface engineering applications.

4-Nitrobenzenesulfonyl Fluoride

349-96-2sc-290457
1 g
$142.00
(0)

4-Nitrobenzenesulfonyl Fluoride is a versatile derivatization agent characterized by its strong electrophilic nature, which enables selective acylation of nucleophiles. The presence of the nitro group enhances its reactivity, facilitating rapid formation of sulfonamide linkages. This compound exhibits unique solubility properties, allowing for effective interactions in various solvents. Its ability to stabilize intermediates through resonance effects contributes to efficient reaction pathways, making it a valuable tool in synthetic chemistry.

Trichloromethyl chloroformate

503-38-8sc-253742
10 ml
$129.00
(0)

Trichloromethyl chloroformate serves as a potent derivatization agent, distinguished by its reactivity as an acid halide. Its electrophilic carbonyl carbon readily engages with nucleophiles, promoting acylation reactions. The presence of three electronegative chlorine atoms enhances its reactivity, leading to rapid formation of esters and carbamates. This compound's unique ability to facilitate selective modifications in complex mixtures makes it an essential reagent in organic synthesis.

Ethanesulfonyl chloride

594-44-5sc-239866
100 ml
$59.00
(0)

Ethanesulfonyl chloride is a highly reactive derivatization agent characterized by its ability to form sulfonamide linkages through nucleophilic substitution. As an acid halide, it exhibits strong electrophilic properties, allowing it to efficiently react with amines and alcohols. The sulfonyl group enhances the stability of the resulting derivatives, facilitating further transformations. Its unique reactivity profile enables selective tagging of functional groups, making it a valuable tool in synthetic organic chemistry.

2-Chloroethyl ethyl ether

628-34-2sc-238001
25 g
$76.00
(0)

2-Chloroethyl ethyl ether serves as a versatile derivatization agent, notable for its ability to engage in nucleophilic substitution reactions. Its ether functionality allows for the formation of stable ether linkages, enhancing the solubility and reactivity of derivatives. The presence of the chloroethyl group promotes selective interactions with nucleophiles, facilitating the formation of complex molecular architectures. This compound's unique reactivity and compatibility with various functional groups make it a significant player in synthetic methodologies.

9-Anthracenecarboxaldehyde

642-31-9sc-214432
sc-214432A
5 g
25 g
$21.00
$53.00
(0)

9-Anthracenecarboxaldehyde is a distinctive derivatization agent characterized by its ability to form stable imine linkages through condensation reactions with amines. Its anthracene moiety enhances π-π stacking interactions, promoting aggregation and influencing reaction kinetics. The aldehyde group facilitates selective electrophilic attacks, allowing for tailored modifications of target molecules. This compound's unique structural features enable diverse synthetic pathways, making it a valuable tool in organic chemistry.

Chloro(dimethyl)phenylsilane

768-33-2sc-252576
5 g
$51.00
(0)

Chloro(dimethyl)phenylsilane serves as a versatile derivatization agent, notable for its ability to introduce silyl groups into organic substrates. Its chlorosilane functionality enables rapid nucleophilic substitution reactions, enhancing reactivity with alcohols and amines. The presence of the dimethylphenyl group contributes to steric hindrance, influencing selectivity and reaction rates. This compound's unique reactivity profile facilitates the formation of siloxane bonds, expanding synthetic possibilities in organosilicon chemistry.

Dichloromethyl(2-phenethyl)silane

772-65-6sc-234598
250 mg
$210.00
(0)

Dichloromethyl(2-phenethyl)silane is a specialized derivatization agent characterized by its unique reactivity due to the presence of both chloromethyl and phenethyl groups. This compound exhibits strong electrophilic behavior, allowing for efficient nucleophilic attack by various functional groups. Its distinct steric and electronic properties promote selective reactions, enabling the formation of stable silane derivatives. The compound's ability to engage in cross-coupling reactions further enhances its utility in synthetic organic chemistry.

Chlorotriethylsilane

994-30-9sc-255018
sc-255018A
sc-255018B
sc-255018C
sc-255018D
5 g
25 g
50 g
100 g
500 g
$37.00
$142.00
$190.00
$300.00
$750.00
(0)

Chlorotriethylsilane serves as a versatile derivatization agent, notable for its ability to form stable silyl ethers through its reactive chlorosilane functionality. This compound facilitates the transformation of alcohols and amines into silyl derivatives, enhancing their volatility and stability for analytical applications. Its unique steric hindrance and electronic characteristics promote selective reactions, making it an effective tool for improving the resolution of complex mixtures in various analytical techniques.