The chemical class known as DDX42 inhibitors encompasses a set of compounds strategically designed to modulate cellular processes associated with DDX42. One such inhibitor is Camptothecin, a topoisomerase I inhibitor that alters DNA topology, potentially influencing processes associated with DDX42. Another compound, Ellipticine, acts as an intercalating agent impacting DNA structure, with potential indirect effects on DDX42 by influencing DNA-related processes. Additionally, NSC 663284, a DNA-binding small molecule, modulates DNA structure, potentially affecting processes linked to DDX42. Bleomycin, an inducer of DNA damage, may have an indirect impact on DDX42 by influencing DNA repair mechanisms. Acridine Orange, a fluorescent dye intercalating with DNA, could potentially affect DDX42 by influencing DNA structure and related processes.
Furthermore, the chemical class includes topoisomerase inhibitors such as Mitoxantrone and Amsacrine, which alter DNA topology and may influence processes associated with DDX42. Anthracycline antibiotics like Daunorubicin and Doxorubicin impact DNA structure, potentially affecting DDX42 through DNA-related processes. Mithramycin A, a DNA-binding antibiotic, modulates DNA structure, potentially influencing DDX42. Suramin, a broad-spectrum kinase inhibitor, modulates signaling pathways and may indirectly impact DDX42 through its effects on cellular processes. Trichostatin A, an HDAC inhibitor, impacts chromatin structure, potentially indirectly influencing DDX42 through its effects on DNA-related processes. Together, these inhibitors provide a diverse array of tools to explore and understand the intricate cellular processes associated with DDX42, offering valuable insights for future research in this field.
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