DDHD1 is a phospholipase involved in the metabolism and signaling of lipids, and its activity can be influenced by compounds that modulate intracellular signaling cascades. For instance, agents that elevate intracellular cAMP levels can enhance DDHD1's activity by altering lipid signaling pathways; this is particularly relevant as cAMP is a key secondary messenger that mediates various cellular responses. Similarly, substances that activate protein kinase C have the potential to phosphorylate and thus modulate DDHD1's function, especially considering PKC's role in the dynamic regulation of lipid metabolism. Additionally, compounds that can increase intracellular calcium concentrations may also modulate the activity of DDHD1, as calcium is a crucial regulator of numerous enzymes involved in lipid metabolism. The interplay between calcium levels and lipid signaling enzymes is intricate and can lead to a modulation of DDHD1's activity, reflecting the protein's sensitivity to changes in cellular lipid composition and signaling.
Moreover, the activity of DDHD1 can be influenced by bioactive lipids that act as signaling molecules within the cell. Certain sphingolipids, for example, can regulate DDHD1 activity through their involvement in sphingolipid signaling pathways, which are integral to various aspects of cell function, including proliferation and apoptosis. Other lipid second messengers are known to play pivotal roles in signal transduction and may enhance DDHD1 activity within their respective metabolic pathways. Additionally, fatty acid derivatives may activate DDHD1 through their participation in complex lipid signaling cascades. Endocannabinoids, which are integral to the endocannabinoid system's signaling processes, could also influence DDHD1 activity through their interactions with lipid signaling pathways. Finally, compounds that increase the levels of secondary messengers like cyclic ADP-ribose, which is involved in calcium release from intracellular stores, may indirectly interact with lipid signaling pathways that involve DDHD1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels, which can enhance DDHD1 activity by altering lipid signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), which may phosphorylate and modulate DDHD1 function in phospholipid metabolism. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Increases intracellular calcium levels, potentially modulating DDHD1 activity as calcium can affect lipid metabolism enzymes. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Calcium ionophore that raises intracellular calcium, possibly affecting DDHD1's role in lipid metabolism and signaling. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Beta-adrenergic agonist that elevates cAMP, which could positively influence DDHD1's lipid signaling-related activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
A bioactive lipid that can regulate DDHD1 activity through its role in sphingolipid signaling pathways. | ||||||
C2 Ceramide | 3102-57-6 | sc-201375 sc-201375A | 5 mg 25 mg | $77.00 $316.00 | 12 | |
Serves as a lipid second messenger, could modify DDHD1 activity within ceramide signaling pathways. | ||||||
1,2-Dimyristoyl-rac-glycerol | 20255-94-1 | sc-220511 | 1 g | $408.00 | ||
Acts as a second messenger in signal transduction, potentially enhancing DDHD1 activity in lipid metabolism. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $90.00 $235.00 $4243.00 | 9 | |
Precursor in eicosanoid synthesis, may activate DDHD1 through modulation of lipid signaling cascades. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $88.00 $190.00 | 1 | |
Enhances lipid signaling and could indirectly activate DDHD1 as it is involved in lipid metabolism. | ||||||