Date published: 2026-4-24

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DDB Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DDB Antibodies for investigating DNA damage-binding proteins. DDB Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA damage-binding proteins are crucial for the cellular response to DNA damage, playing a significant role in maintaining genomic stability and regulating cell cycle progression. Understanding DNA damage-binding proteins is essential for cancer biology research and developing new therapeutic approaches. DDB proteins participate in nucleotide excision repair and help cells recognize and respond to UV-induced DNA damage. Studying DDB proteins can reveal important insights about cellular mechanisms that protect genomic integrity. Research focusing on DNA damage-binding proteins continues to expand knowledge about DNA repair pathways and their regulation. Investigating these molecular mechanisms helps identify potential therapeutic targets for cancer treatment. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of DNA damage response and repair mechanisms.

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DDB Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DDB1 Antibody (E-11)

sc-376860mouse IgG1 κ9-45 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(12)

DDB1 Antibody (B-1)

sc-137142mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
3
(4)

DDB1 Antibody (C-2)

sc-137132mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
3
(3)

DDB2 Antibody (2246C4a)

sc-81246mouse IgG1 κN-Terminal (h)WB, IP, IF, FCMh
14
(5)

DDB CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDB1 CRISPR/Cas9 KO Plasmid (h)

sc-402067hGene KnockoutGFP0
(0)

DDB1 HDR Plasmid (h)

sc-402067-HDRhHomology Directed RepairPuromycin0
(0)

DDB1 Double Nickase Plasmid (h)

sc-402067-NIChGene KnockoutPuromycin0
(0)

DDB1 Double Nickase Plasmid (h2)

sc-402067-NIC-2hGene KnockoutPuromycin0
(0)

DDB1 CRISPR/Cas9 KO Plasmid (m)

sc-419966mGene KnockoutGFP0
(0)

DDB1 HDR Plasmid (m)

sc-419966-HDRmHomology Directed RepairPuromycin0
(0)

DDB2 CRISPR/Cas9 KO Plasmid (h)

sc-401686hGene KnockoutGFP
1
(0)

DDB2 HDR Plasmid (h)

sc-401686-HDRhHomology Directed RepairPuromycin
1
(0)

DDB2 Double Nickase Plasmid (h)

sc-401686-NIChGene KnockoutPuromycin
1
(0)

DDB2 Double Nickase Plasmid (h2)

sc-401686-NIC-2hGene KnockoutPuromycin
1
(0)

DDB CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDB1 CRISPR Activation Plasmid (h)

sc-402067-ACThGene ActivationPuro, Blast, Hygro0
(0)

DDB1 CRISPR Activation Plasmid (m)

sc-419966-ACTmGene ActivationPuro, Blast, Hygro0
(0)

DDB1 CRISPR Activation Plasmid (m2)

sc-419966-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

DDB1 Lentiviral Activation Particles (m)

sc-419966-LACmGene ActivationPuro, Blast, Hygro0
(0)

DDB2 CRISPR Activation Plasmid (h)

sc-401686-ACThGene ActivationPuro, Blast, Hygro
1
(0)

DDB siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDB1 siRNA (h)

sc-37797hGene SilencingN/A0
(0)

DDB1 shRNA Plasmid (h)

sc-37797-SHhGene SilencingPuromycin0
(0)

DDB1 shRNA (h) Lentiviral Particles

sc-37797-VhGene SilencingPuromycin0
(0)

DDB1 siRNA (m)

sc-37798mGene SilencingN/A
1
(0)

DDB1 shRNA Plasmid (m)

sc-37798-SHmGene SilencingPuromycin
1
(0)

DDB1 shRNA (m) Lentiviral Particles

sc-37798-VmGene SilencingPuromycin
1
(0)

DDB2 siRNA (h)

sc-37799hGene SilencingN/A
5
(0)

DDB2 shRNA Plasmid (h)

sc-37799-SHhGene SilencingPuromycin
5
(0)

DDB2 shRNA (h) Lentiviral Particles

sc-37799-VhGene SilencingPuromycin
5
(0)

DDB2 siRNA (m)

sc-37800mGene SilencingN/A0
(0)

DDB2 shRNA Plasmid (m)

sc-37800-SHmGene SilencingPuromycin0
(0)

DDB2 shRNA (m) Lentiviral Particles

sc-37800-VmGene SilencingPuromycin0
(0)