Date published: 2026-5-13

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DAZAP1 Inhibitors

DAZAP1 inhibitors represent a class of compounds with the ability to modulate the function of Deleted in Azospermia Associated Protein 1 (DAZAP1), an RNA-binding protein that plays a critical role in pre-mRNA splicing. DAZAP1 interacts with both DNA and RNA and is involved in various cellular processes, making the inhibitors of this protein potentially influential in a wide range of biochemical activities. Direct inhibitors of DAZAP1 can function by impeding the protein's ability to interact with its binding partners or by affecting its RNA-binding activity. Such inhibitors might bind to the protein's active sites, preventing interaction with RNA and thus inhibiting DAZAP1's function in pre-mRNA splicing. Alternatively, they could bind to allosteric sites on the protein, altering its conformation and potentially reducing its RNA-binding activity. Some compounds could also compete with RNA for binding to DAZAP1, thereby inhibiting its function. Indirect inhibitors of DAZAP1 could influence the cellular processes or pathways that regulate the activity or expression of DAZAP1. For instance, compounds that modulate RNA splicing, a process in which DAZAP1 is involved, could indirectly impact DAZAP1 activity. Chemicals that affect the synthesis, degradation, or function of RNA could also potentially influence DAZAP1 function indirectly.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Spliceostatin A

391611-36-2sc-507481
1 mg
$1800.00
(0)

This compound is known to inhibit the splicing machinery, potentially influencing the activity of DAZAP1 indirectly.

Pladienolide B

445493-23-2sc-391691
sc-391691B
sc-391691A
sc-391691C
sc-391691D
sc-391691E
0.5 mg
10 mg
20 mg
50 mg
100 mg
5 mg
$299.00
$5699.00
$11099.00
$25500.00
$66300.00
$2875.00
63
(2)

A class of compounds known to inhibit splicing, potentially affecting DAZAP1 activity indirectly.

Herboxidiene

142861-00-5sc-506378
1 mg
$1009.00
(0)

This compound inhibits pre-mRNA splicing, potentially affecting DAZAP1 indirectly.

Isoginkgetin

548-19-6sc-507430
5 mg
$225.00
(0)

A pre-mRNA splicing inhibitor, potentially influencing DAZAP1 indirectly.