Date published: 2025-12-6

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D2HGDH Antibodies

Santa Cruz Biotechnology delivers a wide array of D2HGDH monoclonal antibodies for investigating D2-hydroxyglutarate dehydrogenase (D2HGDH) in various biological processes. Multiple experimental applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). D2HGDH is a key enzyme involved in the metabolism of D-2-hydroxyglutarate, a metabolite implicated in several pathological conditions, including cancer and neurodegenerative diseases. By regulating D-2-hydroxyglutarate levels, D2HGDH plays a crucial role in cellular energy production and redox balance. Understanding D2HGDH function is essential for identifying potential therapeutic targets and biomarkers in various diseases. Researchers can utilize specific monoclonal antibodies to examine D2HGDH expression patterns across different tissues and cellular compartments. Advanced imaging techniques combined with D2HGDH monoclonal antibodies enable detailed visualization of protein localization and interactions. Secondary antibodies conjugated to horseradish peroxidase (HRP), phycoerythrin (PE), or fluorescein isothiocyanate (FITC) provide flexible detection options. Santa Cruz Biotechnology monoclonal antibodies for D2HGDH research contribute to advancing scientific understanding of metabolic disorders and potential therapeutic interventions.

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D2HGDH Antibodies

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D2HGDH Antibody (E-6)

sc-514171mouse IgG2a κ41-146 (h)WB, IP, IF, ELISAh

new

(1)

D2HGDH CRISPR Knockout, HDR and Double Nickase Plasmids

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D2HGDH CRISPR/Cas9 KO Plasmid (h)

sc-409421hGene KnockoutGFP0
(0)

D2HGDH HDR Plasmid (h)

sc-409421-HDRhHomology Directed RepairPuromycin0
(0)

D2HGDH Double Nickase Plasmid (h)

sc-409421-NIChGene KnockoutPuromycin0
(0)

D2HGDH Double Nickase Plasmid (h2)

sc-409421-NIC-2hGene KnockoutPuromycin0
(0)

D2HGDH CRISPR/Cas9 KO Plasmid (m)

sc-430204mGene KnockoutGFP0
(0)

D2HGDH HDR Plasmid (m)

sc-430204-HDRmHomology Directed RepairPuromycin0
(0)

D2HGDH Double Nickase Plasmid (m)

sc-430204-NICmGene KnockoutPuromycin0
(0)

D2HGDH Double Nickase Plasmid (m2)

sc-430204-NIC-2mGene KnockoutPuromycin0
(0)

D2HGDH CRISPR Activation Products

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D2HGDH CRISPR Activation Plasmid (h)

sc-409421-ACThGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH CRISPR Activation Plasmid (h2)

sc-409421-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH Lentiviral Activation Particles (h)

sc-409421-LAChGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH Lentiviral Activation Particles (h2)

sc-409421-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH CRISPR Activation Plasmid (m)

sc-430204-ACTmGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH CRISPR Activation Plasmid (m2)

sc-430204-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH Lentiviral Activation Particles (m)

sc-430204-LACmGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH Lentiviral Activation Particles (m2)

sc-430204-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

D2HGDH siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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D2HGDH siRNA (m)

sc-142809mGene SilencingN/A0
(0)

D2HGDH shRNA Plasmid (m)

sc-142809-SHmGene SilencingPuromycin0
(0)

D2HGDH shRNA (m) Lentiviral Particles

sc-142809-VmGene SilencingPuromycin0
(0)