Cyclin YL1 inhibitors belong to a distinctive class of chemical compounds that specifically target the cyclin YL1 protein, a key regulator in the cell cycle progression. The cell cycle, a tightly orchestrated series of events governing cell division, is crucial for maintaining cellular integrity and ensuring proper growth and development. Cyclin YL1, identified as a member of the cyclin family, plays a pivotal role in modulating the activity of cyclin-dependent kinases (CDKs), which are central to cell cycle control. The inhibitors designed to interact with cyclin YL1 are characterized by their unique chemical structures, carefully engineered to disrupt the binding interface between cyclin YL1 and CDKs.
Cyclin YL1 inhibitors involves interference with the formation of cyclin YL1-CDK complexes, thereby impeding the phosphorylation events required for cell cycle progression. These inhibitors exhibit high selectivity for cyclin YL1, distinguishing them from other compounds targeting related cyclins. Their design often involves a comprehensive understanding of the structural and functional aspects of cyclin YL1, allowing for the rational design of small molecules that can effectively disrupt its interactions with CDKs. The development of cyclin YL1 inhibitors represents a promising avenue in the field of cell cycle modulation, offering researchers valuable tools to probe the intricacies of cell cycle regulation and uncover new avenues for targeted interventions in various cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $72.00 $297.00 | 4 | |
An inhibitor of CDKs which may alter the cell cycle and indirectly affect CCNYL1 by modifying the activity of related cyclins and CDKs. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Targets CDKs and might indirectly modulate CCNYL1 activity through cell cycle arrest by inhibiting related CDKs. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
A CDK inhibitor that may interfere with cell cycle regulators and indirectly influence CCNYL1 function. | ||||||
Olomoucine | 101622-51-9 | sc-3509 sc-3509A | 5 mg 25 mg | $72.00 $274.00 | 12 | |
Inhibits CDKs and possibly alters related cyclin activity, impacting CCNYL1 indirectly. | ||||||
Indirubin-3′-monoxime | 160807-49-8 | sc-202660 sc-202660A sc-202660B | 1 mg 5 mg 50 mg | $79.00 $321.00 $671.00 | 1 | |
An inhibitor of CDKs, potentially affecting cyclin-dependent processes and thereby CCNYL1. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
Specifically inhibits CDK4/6 and may indirectly affect CCNYL1 by altering the activity of related cyclins. | ||||||
AT-7519 Hydrochloride | 902135-91-5 | sc-482715 | 5 mg | $125.00 | ||
Targets multiple CDKs and may indirectly influence CCNYL1 by modulating cell cycle progression. | ||||||
Dinaciclib | 779353-01-4 | sc-364483 sc-364483A | 5 mg 25 mg | $247.00 $888.00 | 1 | |
A potent CDK inhibitor that might change cell cycle dynamics, potentially affecting CCNYL1 indirectly. | ||||||
PHA-848125 | 802539-81-7 | sc-364581 sc-364581A | 5 mg 10 mg | $304.00 $555.00 | ||
Inhibits various CDKs and might indirectly influence CCNYL1 by altering cell cycle-related cyclins. | ||||||
AZD 5438 | 602306-29-6 | sc-361115 sc-361115A | 10 mg 50 mg | $205.00 $865.00 | ||
Inhibits CDK1, 2, and 9 which may have a downstream effect on CCNYL1 by impacting the cell cycle. | ||||||