Date published: 2026-5-30

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CWH43 Activators

Common CWH43 Activators include, but are not limited to D-Mannose CAS 3458-28-4, Inositol CAS 6917-35-7, Uridine CAS 58-96-8, Cholesterol CAS 57-88-5 and D-erythro-Sphingosine CAS 123-78-4.

CWH43 activators encompass a group of compounds or molecules that promote the activity or expression of the CWH43 protein. CWH43, a relatively lesser-known protein, has been implicated in various cellular processes, especially within the context of lipid metabolism and membrane-related functions. Its precise role may vary among different organisms, but it's often linked with the synthesis and modification of complex lipids, making it an intriguing target for studies on lipid dynamics and homeostasis.

In yeast, CWH43 (Cell Wall Biogenesis 43 C-Terminal Homolog) is implicated in the ceramide synthesis pathway and has been associated with the maintenance of endoplasmic reticulum morphology. The activators of CWH43 could, therefore, play a pivotal role in modulating lipid-related pathways, ensuring the balance and integrity of cellular membranes. The significance of CWH43 goes beyond yeast, as its homologs in higher organisms might play similar or even more complex roles in lipid metabolism. Activation of CWH43 could potentially influence a host of downstream processes, given the critical role lipids play in cellular signaling, membrane dynamics, and energy storage. Understanding the precise mechanisms and impacts of CWH43 activators will require further research and detailed biochemical analyses. Nonetheless, the ability to modulate the function of such a protein, especially in the realm of lipid metabolism, opens up intriguing possibilities for studying fundamental cellular processes and the intricate network of lipid-associated pathways. As research progresses, the repertoire of known CWH43 activators and their potential applications in basic science will likely expand, shedding light on the multifaceted roles of lipids in cellular health and function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-Mannose

3458-28-4sc-211180
sc-211180A
100 g
250 g
$103.00
$161.00
1
(1)

By playing a role in GPI-anchor synthesis, it might influence CWH43's activity.

Uridine

58-96-8sc-296685
sc-296685A
1 g
25 g
$61.00
$100.00
1
(1)

Involved in GPI anchor biosynthesis, may promote CWH43 expression to fulfill biosynthetic needs.

Cholesterol

57-88-5sc-202539C
sc-202539E
sc-202539A
sc-202539B
sc-202539D
sc-202539
5 g
5 kg
100 g
250 g
1 kg
25 g
$27.00
$2809.00
$129.00
$210.00
$583.00
$88.00
11
(1)

May interact with CWH43 during lipid moiety modification of GPI anchors.

D-erythro-Sphingosine

123-78-4sc-3546
sc-3546A
sc-3546B
sc-3546C
sc-3546D
sc-3546E
10 mg
25 mg
100 mg
1 g
5 g
10 g
$90.00
$194.00
$510.00
$2448.00
$9384.00
$15300.00
2
(2)

As a part of sphingolipid metabolism, may interact with CWH43's lipid remodeling activity.

C2 Ceramide

3102-57-6sc-201375
sc-201375A
5 mg
25 mg
$124.00
$460.00
12
(1)

Given its central role in sphingolipid metabolism and CWH43's function in introducing ceramides into GPI anchors, increasing ceramide levels might theoretically augment CWH43 expression or activity to meet cellular demands for ceramide conjugation.