Coronin 1C Activators
Coronin 1C Activators are a class of chemicals that enhance the functional activity of Coronin 1C primarily through influencing the actin cytoskeleton and microtubules, as well as modulating protein phosphorylation events. These activators, which include forskolin and IBMX, act by raising intracellular cAMP levels and activating cAMP-dependent pathways. Coronin 1C is known to associate with the actin cytoskeleton, which can be affected by cAMP-dependent protein kinase (PKA) activity, potentially enhancing the functional activity of Coronin 1C.
Furthermore, Coronin 1C Activators include chemicals that directly bind to actin filaments like cytochalasin D, latrunculin A, jasplakinolide, and phalloidin. These compounds can indirectly affect the function of Coronin 1C, which is involved in actin remodelling. Coronin 1C Activators also include chemicals like okadaic acid and calyculin A that inhibit protein phosphatases 1 and 2A, thereby enhancing protein phosphorylation events and potentially affecting the activity of Coronin 1C. Lastly, Coronin 1C Activators include paclitaxel, taxol, nocodazole, and vinblastine, which influence the stability and assembly of microtubules, a process that Coronin 1C is known to interact with. By interacting with these cellular structures and processes, these activators can enhance the functional activity of Coronin 1C.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels. Coronin 1C is known to associate with the actin cytoskeleton, which can be affected by cAMP-dependent protein kinase (PKA) activity, potentially enhancing the functional activity of Coronin 1C. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective phosphodiesterase inhibitor that raises intracellular cAMP levels. By activating cAMP-dependent pathways, IBMX can indirectly enhance Coronin 1C's function in actin remodeling. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide induces actin polymerization and stabilizes actin filaments, potentially enhancing the functional activity of Coronin 1C, which is involved in actin remodeling. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Phalloidin binds to F-actin, stabilizing actin filaments and inhibiting their depolymerization, which could indirectly affect the function of Coronin 1C, a protein that associates with the actin cytoskeleton. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases 1 and 2A. It can enhance protein phosphorylation events, potentially affecting Coronin 1C's role in actin remodeling. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is a potent inhibitor of protein phosphatases 1 and 2A. By enhancing protein phosphorylation events, it can indirectly affect the function of Coronin 1C. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents depolymerization, potentially influencing Coronin 1C's function, as this protein is known to interact with microtubules. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole depolymerizes microtubules, which can indirectly influence the function of Coronin 1C as it is known to interact with microtubules. | ||||||
Vinblastine Sulfate | 143-67-9 | sc-201447 sc-201447A sc-201447B sc-201447C | 10 mg 50 mg 100 mg 1 g | $109.00 $412.00 $561.00 $2244.00 | 9 | |
Vinblastine binds to tubulin dimers, inhibiting assembly of microtubule structures, which can indirectly influence the function of Coronin 1C as it is known to interact with microtubules. | ||||||