COMMD7 activators encompass a broad spectrum of chemical compounds that influence its function by modulating associated signaling pathways and biological processes. Key among these are compounds that affect copper metabolism, such as Copper (II) sulfate, Disulfiram, and Tetrathiomolybdate. These compounds directly or indirectly modulate the availability of copper ions, a crucial element in the function of COMMD7. By altering copper homeostasis, these compounds can enhance the functional activity of COMMD7, which is intricately involved in copper metabolism and transport. Zinc sulfate, another essential metal ion, similarly impacts COMMD7 activity. It does so by influencing the delicate balance of metal ions within cells, thereby affecting the pathways where COMMD7 is active.
Moreover, compounds like Curcumin, Resveratrol, and Vitamin C play significant roles in modulating oxidative stress and redox signaling pathways. These pathways are closely linked to the regulation of metal ion homeostasis and are thus pivotal in the functional regulation of COMMD7. Curcumin, with its broad-spectrum influence on cellular signaling, and Resveratrol, known for its impact on oxidative stress mechanisms, both contribute to creating an intracellular environment that can enhance COMMD7's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper ions can bind to COMMD proteins, affecting their function. For COMMD7, copper binding can lead to alterations in copper metabolism pathways, potentially enhancing its activity in copper homeostasis. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram can chelate copper, influencing its availability in cells. This can indirectly affect COMMD7 by altering the cellular copper levels, which COMMD7 is known to interact with. | ||||||
Ammonium tetrathiomolybdate | 15060-55-6 | sc-239242 sc-239242A sc-239242B sc-239242C | 1 g 10 g 25 g 50 g | $47.00 $203.00 $421.00 $525.00 | ||
Tetrathiomolybdate forms complexes with copper, potentially affecting COMMD7 activity by modulating copper availability and influencing pathways associated with copper metabolism. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is known to interact with copper metabolism. Zinc sulfate can influence COMMD7 activity indirectly by altering copper homeostasis in cells, where COMMD7 plays a role. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate various signaling pathways, including those related to metal ion homeostasis. It may indirectly influence COMMD7 activity through its effects on these pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol influences several signaling pathways and could indirectly affect COMMD7 by modulating pathways related to oxidative stress and metal ion balance. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Vitamin C can influence metal ion homeostasis and oxidative stress responses. Its action on these pathways could indirectly enhance COMMD7 activity. | ||||||
Methylglyoxal solution | 78-98-8 | sc-250394 sc-250394A sc-250394B sc-250394C sc-250394D | 25 ml 100 ml 250 ml 500 ml 1 L | $146.00 $437.00 $478.00 $754.00 $1446.00 | 3 | |
Methylglyoxal, a glycolysis byproduct, can modify cellular redox states. This could indirectly influence COMMD7 activity by affecting redox-sensitive pathways. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $82.00 $2091.00 | 8 | |
Glutathione, a key antioxidant, can influence redox states in cells. This could indirectly affect COMMD7 by modulating oxidative stress responses, which are part of COMMD7's regulatory network. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, found in green tea, can modulate various signaling pathways, potentially influencing COMMD7 activity through its effects on oxidative stress and metal ion homeostasis. | ||||||