Date published: 2025-12-24

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CLV3 Inhibitors

CLV3 inhibitors constitute a chemical class primarily utilized in plant biology and agriculture to modulate the growth and development of plants. The acronym CLV3 stands for CLAVATA3, which is a key gene in plants responsible for regulating the size and maintenance of the shoot apical meristem (SAM). The SAM is a critical region in plants that houses stem cells and is pivotal for continuous growth and organ formation. CLV3 inhibitors target this specific gene or its downstream signaling pathways to influence the meristem's activity. These chemical compounds exert their effects through various mechanisms, such as interference with hormonal balance. Many CLV3 inhibitors function as synthetic auxins, a class of plant hormones that regulate cell division and differentiation. By mimicking or disrupting auxin signaling, these inhibitors can lead to uncontrolled cell proliferation or inhibited stem cell maintenance within the SAM, ultimately affecting the plant's overall growth and architecture. Additionally, some CLV3 inhibitors target gibberellin biosynthesis or signaling pathways. Gibberellins are another class of plant hormones responsible for promoting stem elongation and growth. By inhibiting gibberellin-related processes, these compounds can induce dwarfing phenotypes and reduced shoot elongation.Overall, CLV3 inhibitors play a crucial role in plant research and agriculture by providing a means to control plant growth, size, and architecture. These chemicals are valuable tools for studying the intricate molecular pathways governing meristem development and, when applied appropriately, can have significant implications for optimizing crop production, enhancing plant breeding programs, and managing vegetation in various agricultural and horticultural settings.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Picloram

1918-02-1sc-250720
250 mg
$110.00
(0)

Picloram inhibits CLV3 by interfering with auxin transport. It disrupts cell division and elongation in the meristem by downregulating the expression of CLV3, leading to reduced stem cell maintenance and a decrease in shoot apical meristem size.

Paclobutrazol

76738-62-0sc-236284
sc-236284A
sc-236284B
250 mg
1 g
5 g
$33.00
$51.00
$144.00
2
(1)

Paclobutrazol inhibits CLV3 by suppressing gibberellin synthesis, which indirectly affects CLV3 expression. It causes dwarfing and reduced stem cell maintenance in meristems by regulating hormone levels and disrupting cell differentiation.

1-Naphthylacetic acid

86-87-3sc-253943
sc-253943A
sc-253943B
sc-253943C
sc-253943D
sc-253943E
25 g
100 g
250 g
1 kg
2.5 kg
5 kg
$24.00
$41.00
$92.00
$326.00
$775.00
$1510.00
(0)

NAA inhibits CLV3 through its role as a synthetic auxin. It promotes excessive cell division and differentiation in the shoot apical meristem, leading to the depletion of stem cell populations and meristem abnormalities.

2,4-Dichlorophenoxy Acetic Acid

94-75-7sc-205097
sc-205097A
sc-205097B
sc-205097C
sc-205097D
10 g
25 g
100 g
250 g
500 g
$25.00
$36.00
$47.00
$92.00
$311.00
1
(0)

2,4-D inhibits CLV3 by acting as a synthetic auxin and disrupting hormonal balance. It induces uncontrolled cell division and growth in the shoot apical meristem, ultimately depleting the stem cell population and affecting meristem development.

Trinexapac-ethyl

95266-40-3sc-229607
100 mg
$92.00
(0)

Trinexapac-ethyl inhibits CLV3 by modulating gibberellin metabolism. It reduces gibberellin levels, leading to decreased stem cell maintenance in the meristem and suppressed shoot elongation.

Ethephon

16672-87-0sc-252788
250 mg
$83.00
(0)

Ethephon indirectly inhibits CLV3 by releasing ethylene gas, which affects auxin transport. It disrupts stem cell maintenance in the meristem by altering hormone dynamics and causing abnormalities in meristem structure.

Quinchlorac

84087-01-4sc-236530
1 g
$56.00
(0)

Quinclorac inhibits CLV3 by disrupting auxin transport. It interferes with cell division and differentiation in the shoot apical meristem, resulting in a decrease in stem cell populations and abnormalities in meristem structure.

Daminozide

1596-84-5sc-326749
sc-326749A
5 g
25 g
$32.00
$80.00
(1)

Daminozide inhibits CLV3 by regulating gibberellin biosynthesis. It reduces gibberellin levels, causing impaired stem cell maintenance in the meristem and stunted shoot elongation.

Uniconazole

83657-22-1sc-205877
sc-205877A
sc-205877B
5 g
10 g
100 g
$128.00
$163.00
$724.00
(2)

Uniconazole inhibits CLV3 by blocking gibberellin biosynthesis. It lowers gibberellin levels, resulting in decreased stem cell maintenance in the meristem and inhibited shoot elongation.