Clusterin-L1 Inhibitors
Clusterin-L1 inhibitors belong to a specialized class of chemical compounds designed to target a specific protein known as Clusterin-L1. Clusterin-L1, also referred to as CLU-L1, is a protein associated with various cellular processes and has been linked to several biological functions within the human body. These inhibitors are engineered to interact with Clusterin-L1, modulating its activity or blocking its function.
At the molecular level, Clusterin-L1 inhibitors typically feature a specific chemical structure that allows them to bind to Clusterin-L1 with high affinity. This binding can result in several downstream effects, such as altering cellular signaling pathways or preventing Clusterin-L1 from performing its natural functions. The primary goal of Clusterin-L1 inhibitors is to influence the behavior of Clusterin-L1, either by suppressing its overactivity in certain disease conditions or by enhancing its function in other situations. The specific mechanisms by which these inhibitors interact with Clusterin-L1 may vary, but they are meticulously designed to have a selective and controlled impact on this protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Clioquinol | 130-26-7 | sc-201066 sc-201066A | 1 g 5 g | $45.00 $115.00 | 2 | |
Clioquinol inhibits Clusterin-L1 by interfering with its metal-binding properties, disrupting its function in metal ion homeostasis and chaperone activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG modulates Clusterin-L1 by promoting its degradation, leading to reduced levels of Clusterin-L1 and preventing its pathological functions. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin interferes with Clusterin-L1 function by reducing its expression and inhibiting its ability to protect cells from stress-induced damage. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein inhibits Clusterin-L1 by reducing its expression and interfering with its chaperone activity, thereby mitigating its protective functions. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits Clusterin-L1 by interfering with its transcription, reducing Clusterin-L1 levels, and suppressing its protective activities. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin suppresses Clusterin-L1 by reducing its expression and inhibiting its chaperone function, preventing its protective effects on cells. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Tannic acid inhibits Clusterin-L1 by binding to its exposed hydrophobic regions, preventing its aggregation and pathological interactions. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Tamoxifen inhibits Clusterin-L1 by disrupting its transcription and reducing its expression, thereby mitigating its protective functions in cells. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin inhibits Clusterin-L1 by binding to its active sites, interfering with its chaperone function, and disrupting its protective activities. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $21.00 $65.00 $120.00 $251.00 $815.00 | 23 | |
EGTA chelates calcium ions, which are essential for Clusterin-L1 function, leading to its inactivation and suppression of its cellular protective role. | ||||||