Date published: 2026-5-13

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Chloride Channel Modulators

Santa Cruz Biotechnology now offers a broad range of chloride channel modulators for use in various applications. Chloride channel modulators are crucial tools in scientific research, enabling the study and manipulation of chloride channels, which are vital for maintaining cellular homeostasis, regulating cell volume, and facilitating neurotransmission. These modulators, which can either inhibit or enhance chloride channel activity, are used extensively to explore the physiological and pathological roles of chloride channels in various tissues and organs. Researchers utilize chloride channel modulators to investigate the mechanisms of ion transport, understand the regulation of intracellular chloride concentration, and elucidate the role of chloride channels in processes such as epithelial fluid secretion and neuronal excitability. Additionally, these modulators are instrumental in the development of experimental models to study diseases associated with chloride channel dysfunction, providing insights into conditions like cystic fibrosis and epilepsy. By offering a comprehensive selection of high-quality chloride channel modulators, Santa Cruz Biotechnology supports cutting-edge research in cell biology, neuroscience, and physiology, empowering scientists to advance their understanding of chloride channel function and regulation. These modulators enable precise control over chloride channel activity, facilitating the discovery of new biological targets and the development of novel experimental approaches. View detailed information on our available chloride channel modulators by clicking on the product name.

Items 11 to 15 of 15 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chromanol 293B

163163-23-3sc-203889
sc-203889A
10 mg
50 mg
$182.00
$774.00
1
(1)

Chromanol 293B acts as a chloride channel modulator by engaging with the channel's regulatory sites, leading to alterations in ion permeability. Its unique structural features allow for specific interactions with amino acid residues, which can shift the channel's activation thresholds. The compound's kinetic profile reveals a rapid onset of action, influencing the channel's response to voltage changes. Additionally, its hydrophobic characteristics promote effective membrane integration, impacting cellular ionic balance.

SFK1

678997-25-6sc-215849
10 mg
$159.00
(0)

SFK1 functions as a chloride channel modulator by selectively binding to allosteric sites on the channel, inducing conformational changes that enhance chloride ion flow. Its unique molecular architecture facilitates specific hydrogen bonding and hydrophobic interactions with channel proteins, fine-tuning their gating mechanisms. The compound exhibits a distinct reaction kinetics profile, characterized by a delayed onset, allowing for prolonged modulation of channel activity under varying physiological conditions.

PG 01

853138-65-5sc-358839
sc-358839A
5 mg
25 mg
$500.00
$750.00
(0)

PG 01 acts as a chloride channel modulator through its ability to interact with specific binding domains on the channel proteins, promoting alterations in their structural dynamics. This compound showcases unique electrostatic interactions that stabilize intermediate states of the channel, influencing ion permeability. Its kinetic behavior is marked by a rapid onset of action, enabling swift adjustments in chloride ion transport, which can be critical in various cellular environments.

Etbicyphat

1005-93-2sc-294479
100 mg
$439.00
(0)

Etbicyphat functions as a chloride channel modulator by selectively engaging with allosteric sites on channel proteins, leading to conformational changes that enhance chloride ion flow. Its unique hydrophobic interactions facilitate the stabilization of channel open states, optimizing ion conductance. The compound exhibits distinctive reaction kinetics, characterized by a gradual activation phase that allows for fine-tuning of chloride transport in response to cellular signals, thereby influencing physiological processes.

Duramycin

1391-36-2sc-239840
10 mg
$590.00
2
(1)

Duramycin acts as a chloride channel modulator by binding to specific sites on channel proteins, inducing structural alterations that promote chloride ion permeability. Its unique ability to form hydrogen bonds enhances the stability of the channel's open conformation, facilitating efficient ion transport. The compound demonstrates a rapid onset of action, with a pronounced effect on ion flux, allowing for dynamic regulation of chloride flow in response to varying cellular conditions.