Ceruloplasmin Activators encompass a range of compounds that, while not directly interacting with ceruloplasmin, can influence its synthesis, stability, and function through various indirect mechanisms. These mechanisms primarily involve modulation of liver function, copper metabolism, and overall protein synthesis. Firstly, several compounds in this class, such as copper sulfate and estrogen, directly influence the synthesis of ceruloplasmin in the liver. Copper is an integral part of ceruloplasmin, and its availability can directly impact the production and stability of this protein. Similarly, hormonal regulation by compounds like estrogen can modulate the synthesis of ceruloplasmin, reflecting the complex interplay between hormonal balance and protein synthesis in the liver.
Secondly, other compounds in this class, such as Vitamin C, Vitamin D, and iron supplements, indirectly affect ceruloplasmin levels by influencing the metabolic pathways related to iron and copper metabolism. Ceruloplasmin's primary function is related to iron transport; thus, alterations in iron homeostasis can trigger compensatory mechanisms affecting ceruloplasmin levels. Additionally, antioxidants like N-acetylcysteine and polyphenols from green tea can modulate the oxidative stress status in cells, which might impact the synthesis and functionality of ceruloplasmin. In conclusion, the chemical class of "ceruloplasmin activators" is defined not by direct stimulation of the protein but by their influence on the various physiological, metabolic, and environmental factors that govern ceruloplasmin's synthesis and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Copper sulfate can increase the synthesis of ceruloplasmin as it is a major source of copper, which is an essential component of this protein. Adequate copper levels are necessary for the proper function and stability of ceruloplasmin. | ||||||
Conjugated Estrogen | 12126-59-9 | sc-357319 sc-357319A | 25 mg 100 mg | $150.00 $459.00 | ||
Estrogen can influence ceruloplasmin levels indirectly. Estrogen has been shown to increase the synthesis of ceruloplasmin in the liver, possibly due to its effect on liver metabolism and protein synthesis. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a derivative of vitamin A, can influence gene expression. It might enhance the expression of ceruloplasmin by modulating gene transcription in the liver, where ceruloplasmin is primarily synthesized. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc competes with copper for absorption in the body. The administration of zinc sulfate can lead to altered copper metabolism and potentially influence ceruloplasmin levels as the body attempts to regulate copper homeostasis. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
L-Ascorbic acid can potentially influence ceruloplasmin levels as it plays a role in copper metabolism and iron absorption, both of which are closely related to ceruloplasmin function. | ||||||
Ferrous Sulfate (Iron II Sulfate) Heptahydrate | 7782-63-0 | sc-211505 sc-211505A | 250 g 500 g | $72.00 $107.00 | ||
Iron supplementation can indirectly influence ceruloplasmin levels, as ceruloplasmin is involved in iron metabolism. Increased iron levels might stimulate the liver to produce more ceruloplasmin for iron transport. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol, through its role in gene regulation and liver function, might influence ceruloplasmin synthesis indirectly. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium, being an essential trace element, is involved in various metabolic pathways and can influence the synthesis of proteins like ceruloplasmin. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
As an antioxidant, N-acetylcysteine can influence the redox state of cells, potentially affecting the synthesis and stability of proteins like ceruloplasmin. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Polyphenols in green tea, like EGCG, can modulate liver metabolism and oxidative stress, potentially influencing ceruloplasmin levels. | ||||||