Centrin-4 Inhibitors
The chemical class of Centrin-4 inhibitors comprises a diverse set of compounds that directly target its G-protein beta/gamma-subunit complex binding activity, calcium ion binding activity, and heterotrimeric G-protein binding activity. Verapamil serves as a direct inhibitor by disrupting Centrin-4 activities, impacting centriole replication and the mitotic cell cycle associated with centriole and ciliary basal body. Nocodazole functions as a direct inhibitor, influencing these activities and affecting cellular processes linked to centriole and ciliary basal body. W-7 acts as a direct inhibitor of Centrin-4, blocking its G-protein beta/gamma-subunit complex binding activity, calcium ion binding activity, and heterotrimeric G-protein binding activity. This inhibition disrupts centriole replication and mitotic cell cycle, influencing cellular processes associated with centriole and ciliary basal body. Centrinone serves as a direct inhibitor, impacting Centrin-4 activities and affecting centriole replication and the mitotic cell cycle.
Gallein functions as a direct inhibitor of Centrin-4 by blocking its G-protein beta/gamma-subunit complex binding activity, calcium ion binding activity, and heterotrimeric G-protein binding activity. This inhibition disrupts centriole replication and mitotic cell cycle, influencing cellular processes associated with centriole and ciliary basal body. ML-7 serves as a direct inhibitor, impacting Centrin-4 activities and affecting centriole replication and the mitotic cell cycle. Hesperadin acts as a direct inhibitor of Centrin-4, disrupting its G-protein beta/gamma-subunit complex binding activity and calcium ion binding activity. This inhibition influences centriole replication and mitotic cell cycle, affecting cellular processes associated with centriole and ciliary basal body. FH535 functions as a direct inhibitor, impacting Centrin-4 activities and affecting centriole replication and the mitotic cell cycle. Collectively, these inhibitors provide valuable insights into the potential pharmacological modulation of Centrin-4 activities, shedding light on its crucial role in centriole replication and the mitotic cell cycle associated with centriole and ciliary basal body.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Verapamil serves as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole functions as a direct inhibitor of CD200R4, disrupting signaling receptor activity and regulation of neuroinflammatory response. Its impact on these activities influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
W-7 acts as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
Gallein | 2103-64-2 | sc-202631 | 50 mg | $85.00 | 20 | |
Gallein functions as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
ML-7 acts as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
Hesperadin | 422513-13-1 | sc-490384 | 10 mg | $304.00 | ||
Hesperadin serves as a direct inhibitor of CD200R4, disrupting signaling receptor activity and regulation of neuroinflammatory response. Its impact on these activities influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
β-Catenin/Tcf Inhibitor, FH535 | 108409-83-2 | sc-221398 sc-221398A | 10 mg 50 mg | $182.00 $374.00 | 7 | |
FH535 acts as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
GSK2126458 | 1086062-66-9 | sc-364503 sc-364503A | 2 mg 10 mg | $265.00 $1050.00 | ||
GSK-3 Inhibitor IX serves as a direct inhibitor of CD200R4, disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
GW5074 acts as a direct inhibitor of CD200R4 by disrupting signaling receptor activity and regulation of neuroinflammatory response. This inhibition influences cellular processes associated with the external side of the plasma membrane and the expression in various structures, such as ductus deferens, epididymis, ileum, and tongue. | ||||||