Cell Signaling
Items 111 to 120 of 496 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Loratadine | 79794-75-5 | sc-203117 sc-203117A | 10 mg 50 mg | $107.00 $455.00 | 1 | |
Loratadine functions as a selective antagonist in cell signaling by modulating histamine receptor activity. Its unique molecular structure allows it to effectively block H1 receptors, preventing histamine-induced signaling cascades. This inhibition alters intracellular calcium levels and downstream signaling pathways, influencing cellular responses such as inflammation and neurotransmission. The compound's kinetic profile reveals a rapid onset of action, with prolonged receptor binding that stabilizes its effects on cellular communication. | ||||||
PS-1145 dihydrochloride | 431898-65-6 (free base) | sc-301621 sc-301621A | 5 mg 25 mg | $109.00 $440.00 | 5 | |
PS-1145 dihydrochloride acts as a potent modulator in cell signaling by selectively influencing specific protein interactions. Its unique ability to disrupt protein-protein interactions alters downstream signaling pathways, particularly those involved in cellular proliferation and differentiation. The compound exhibits distinct reaction kinetics, characterized by a rapid association and a gradual dissociation from target proteins, leading to sustained effects on cellular behavior. This dynamic interaction profile enhances its role in regulating complex signaling networks. | ||||||
L-Cycloserine | 339-72-0 | sc-201387A sc-201387 | 25 mg 100 mg | $215.00 $300.00 | 4 | |
L-Cycloserine functions as a unique signaling molecule by mimicking natural amino acids, thereby influencing receptor activation and downstream signaling cascades. Its structural similarity allows it to engage in specific hydrogen bonding and electrostatic interactions with target proteins, modulating their activity. This compound exhibits a distinctive binding affinity, leading to altered kinetics in cellular responses, which can significantly impact metabolic pathways and gene expression regulation. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $71.00 $291.00 | 4 | |
Purvalanol A is a potent inhibitor of cyclin-dependent kinases (CDKs), specifically targeting CDK2 and CDK1. By binding to the ATP-binding site, it disrupts the phosphorylation of key substrates involved in cell cycle regulation. This inhibition alters downstream signaling pathways, affecting cellular proliferation and differentiation. Its selective interaction with CDKs underscores its role in modulating cell cycle dynamics and influencing cellular responses to growth signals. | ||||||
2′,7′-Dichlorodihydrofluorescein Diacetate | 4091-99-0 | sc-359840 sc-359840A sc-359840B | 100 mg 250 mg 500 mg | $104.00 $190.00 $328.00 | 40 | |
2′,7′-Dichlorodihydrofluorescein Diacetate serves as a vital indicator in cellular signaling by undergoing deacetylation and oxidation within cells, resulting in a fluorescent signal. This transformation allows for real-time monitoring of reactive oxygen species (ROS) levels, facilitating insights into oxidative stress pathways. Its unique ability to selectively react with specific radicals enhances its utility in studying cellular responses and metabolic changes, providing a dynamic view of intracellular environments. | ||||||
Chymostatin | 9076-44-2 | sc-202541 sc-202541A sc-202541B sc-202541C sc-202541D | 5 mg 10 mg 25 mg 50 mg 100 mg | $153.00 $255.00 $627.00 $1163.00 $2225.00 | 3 | |
Chymostatin is a potent inhibitor of serine proteases, influencing cell signaling by modulating proteolytic pathways. Its unique ability to bind selectively to active sites of enzymes alters substrate availability, thereby affecting downstream signaling cascades. This interaction can lead to changes in cellular responses, including apoptosis and proliferation. By stabilizing specific protein conformations, Chymostatin plays a crucial role in regulating cellular homeostasis and communication. | ||||||
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $138.00 $530.00 | 24 | |
Prostratin is a unique compound that engages with cellular signaling pathways by activating protein kinase C (PKC) isoforms. Its interaction with these kinases initiates a cascade of phosphorylation events, influencing gene expression and cellular responses. Prostratin's ability to modulate the activity of transcription factors enhances the signaling network, promoting diverse biological outcomes. This dynamic engagement with cellular machinery underscores its role in fine-tuning cellular communication and function. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $145.00 $450.00 | 11 | |
Capsazepine is a selective antagonist of the transient receptor potential vanilloid 1 (TRPV1) channel, crucial for nociceptive signaling. By binding to the TRPV1 receptor, it inhibits calcium influx, disrupting pain signaling pathways. This modulation affects neuronal excitability and alters intracellular calcium dynamics, leading to changes in neurotransmitter release. Its unique interaction with TRPV1 highlights its role in regulating sensory neuron activity and cellular signaling mechanisms. | ||||||
L-3,3′,5-Triiodothyronine, Sodium Salt | 55-06-1 | sc-205725 | 250 mg | $113.00 | ||
L-3,3′,5-Triiodothyronine, Sodium Salt, functions as a critical modulator in cellular signaling by interacting with nuclear receptors, influencing gene expression and metabolic processes. Its unique tri-iodinated structure enhances binding affinity, facilitating rapid signal transduction. This compound activates distinct pathways, including those regulating energy metabolism and thermogenesis, thereby impacting cellular homeostasis and adaptive responses to environmental changes. | ||||||
Papaverine hydrochloride | 61-25-6 | sc-202273 | 5 g | $51.00 | 4 | |
Papaverine hydrochloride acts as a potent modulator of intracellular signaling by inhibiting phosphodiesterase enzymes, leading to increased levels of cyclic AMP. This elevation in cyclic AMP enhances various signaling cascades, promoting smooth muscle relaxation and influencing neurotransmitter release. Its unique ability to traverse cellular membranes allows for rapid distribution within tissues, facilitating diverse physiological responses and contributing to the regulation of vascular tone and cellular communication. | ||||||