Date published: 2026-3-3

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Cdk Inhibitors

Santa Cruz Biotechnology now offers a broad range of Cdk Inhibitors for use in various applications. Cyclin-dependent kinases (Cdks) are a family of serine/threonine protein kinases that play a central role in regulating the cell cycle, controlling the progression through various phases, and ensuring accurate cell division. Cdk Inhibitors are indispensable tools in scientific research, as they enable the detailed study of cell cycle regulation, providing insights into the mechanisms that control cell proliferation, differentiation, and apoptosis. By selectively inhibiting Cdks, researchers can explore the functional roles of specific Cdks in various cellular processes, including the timing of cell cycle transitions, DNA replication, and response to cellular stress. These inhibitors are widely used in biochemical assays, cell culture studies, and in vivo models to dissect the contributions of different Cdks in maintaining cellular homeostasis and understanding how their dysregulation can lead to abnormal cell growth. Cdk Inhibitors are also employed to study the complex interactions between Cdks and their regulatory partners, such as cyclins and Cdk inhibitors (CKIs), which are crucial for maintaining the integrity of the cell cycle. The availability of these inhibitors has facilitated research across multiple disciplines, including molecular biology, cancer research, and developmental biology, where understanding the regulation of the cell cycle is essential for advancing knowledge of cellular processes and their implications in disease. View detailed information on our available Cdk Inhibitors by clicking on the product name.

Items 21 to 22 of 22 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PHA-793887

718630-59-2sc-364580
sc-364580A
5 mg
10 mg
$189.00
$432.00
(0)

PHA-793887 acts as a selective inhibitor of cyclin-dependent kinases (Cdks), showcasing a unique binding affinity that disrupts the ATP-binding pocket. Its distinct molecular architecture allows for specific interactions with regulatory motifs, leading to altered kinase conformations. This compound exhibits a unique kinetic profile, demonstrating a time-dependent inhibition mechanism that influences the phosphorylation cascade, thereby modulating cell cycle progression and regulatory networks.

PHA-848125

802539-81-7sc-364581
sc-364581A
5 mg
10 mg
$304.00
$555.00
(0)

PHA-848125 acts as a selective inhibitor of cyclin-dependent kinases (Cdks) by engaging in unique molecular interactions that disrupt the kinase's catalytic activity. Its specific binding affinity to the ATP-binding pocket alters the conformational dynamics of the enzyme, leading to a decrease in phosphorylation events. The compound's distinct steric properties and electronic characteristics contribute to its ability to modulate kinase activity with precision, influencing cellular regulatory mechanisms.