The inhibitors listed above target various cellular processes that are indirectly related to the function of CDC11, especially in the context of cell division, cytokinesis, and septin ring assembly. Latrunculin A and Cytochalasin D, by disrupting actin filaments and inhibiting actin polymerization, respectively, can influence the cytokinesis process in which CDC11 is involved. Nocodazole and Benomyl target microtubule dynamics, which are crucial for cell division, potentially impacting CDC11 function. Compounds like Forskolin and PD98059, which affect signaling pathways, might indirectly influence the regulatory mechanisms involving CDC11.
Myriocin, affecting sphingolipid biosynthesis, and Lovastatin, targeting lipid metabolism, could influence membrane dynamics and indirectly CDC11's function. Rapamycin, as an mTOR inhibitor, affects protein synthesis and cell growth, which are essential for cell division processes involving CDC11. Mitomycin C and Hydroxyurea, which interfere with DNA synthesis and crosslinking, could impact the cell cycle and, consequently, CDC11-related pathways. Staurosporine, being a broad-spectrum kinase inhibitor, might also affect signaling pathways related to CDC11's function in cytokinesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A disrupts actin filaments, potentially influencing the assembly or function of the septin ring, in which CDC11 is involved. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D inhibits actin polymerization, which can affect cytokinesis and indirectly impact CDC11 function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule dynamics, potentially influencing cell division processes involving CDC11. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, potentially affecting cAMP levels and signaling pathways involved in cell division, indirectly impacting CDC11. | ||||||
Myriocin (ISP-1) | 35891-70-4 | sc-201397 | 10 mg | $150.00 | 8 | |
Myriocin, a sphingolipid biosynthesis inhibitor, may affect membrane dynamics and indirectly influence CDC11 function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a MEK inhibitor, can affect MAP kinase pathways, potentially influencing signaling pathways related to CDC11 function. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $29.00 $90.00 $339.00 | 12 | |
Lovastatin inhibits HMG-CoA reductase, potentially affecting lipid metabolism and indirectly CDC11's role in cell division. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, might affect protein synthesis and cell growth, potentially impacting CDC11 function. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
Mitomycin C is an antitumor antibiotic that can crosslink DNA, potentially affecting cell division and indirectly CDC11. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, affecting DNA synthesis, and potentially influencing CDC11-related pathways. | ||||||