CD97 Activators
CD97 Activators are a collection of diverse chemical compounds that enhance the functional activity of CD97, a protein implicated in various immune and vascular system functions. The activation of CD97 is closely linked to G protein-coupled receptor (GPCR) signaling pathways. Compounds like Lysophosphatidic Acid (LPA) and D-erythro-Sphingosine-1-phosphate play pivotal roles in enhancing CD97 activity. LPA acts through its GPCRs to amplify CD97-mediated processes in cell adhesion and migration, while D-erythro-Sphingosine-1-phosphate enhances CD97 signaling in immune cell trafficking and vascular regulation. Additionally, Forskolin and IBMX, by elevating intracellular cAMP levels, indirectly support CD97 signaling in immune responses, highlighting the interplay between cAMP and GPCR pathways in modulating CD97 functions.
Further contributing to the modulation of CD97 activity are compounds that influence various aspects of immune and vascular responses. PGE2, U-46619, a thromboxane A2 analog, and Adenosine, each interacting with specific GPCRs, enhance CD97's role in immune modulation and vascular functions. Rolipram, a selective phosphodiesterase-4 inhibitor, and Cilostazol, targeting phosphodiesterase-3, also increase cAMP levels, supporting CD97 in immune cell signaling. Additionally, NECA, an adenosine receptor agonist, and Endothelin-1, acting through endothelin receptors, contribute to CD97 activation in immune and vascular responses. Histamine, free base, through its receptor-mediated signaling, further underscores the complex regulatory network influencing CD97 activity in immune signaling and inflammatory responses. Collectively, these CD97 Activators, through their targeted effects on GPCR signaling and cAMP modulation, play a crucial role in enhancing the functionality of CD97, highlighting its significance in immune and vascular system regulation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA, acting through its G protein-coupled receptors, can enhance the signaling pathways involving CD97, leading to increased functional activity in processes like cell adhesion and migration. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
D-erythro-Sphingosine-1-phosphate, through its interaction with sphingosine-1-phosphate receptors, can indirectly enhance CD97-mediated signaling in immune cell trafficking and vascular system regulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin elevates intracellular cAMP levels, which can indirectly enhance CD97 signaling by modulating G protein-coupled receptor pathways involved in immune responses. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX, a nonspecific inhibitor of phosphodiesterases, raises cAMP levels, indirectly supporting CD97-mediated signaling in immune cell function and migration. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 interacts with its G protein-coupled receptors, potentially enhancing CD97 activity in modulating immune responses and inflammation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
As a selective phosphodiesterase-4 inhibitor, Rolipram increases cAMP levels, potentially enhancing CD97 functionality in immune cell signaling. | ||||||
U-46619 | 56985-40-1 | sc-201242 sc-201242A | 1 mg 10 mg | $245.00 $1301.00 | 40 | |
U-46619, a thromboxane A2 analog, can enhance GPCR-mediated signaling pathways, potentially increasing CD97 activity in thrombosis and vascular functions. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine, through its interaction with adenosine receptors, can indirectly enhance CD97-mediated signaling in immune modulation and vascular responses. | ||||||
Cilostazol | 73963-72-1 | sc-201182 sc-201182A | 10 mg 50 mg | $109.00 $322.00 | 3 | |
Cilostazol, by inhibiting phosphodiesterase-3, increases cAMP levels, indirectly supporting CD97 function in immune cell signaling and vascular regulation. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine, free base, acting through its receptors, can modulate G protein-coupled receptor pathways, potentially enhancing CD97's role in immune cell signaling and inflammatory responses. | ||||||