CD83 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A potent inhibitor of PI3K, LY294002 disrupts the PI3K/Akt pathway, crucial in various cellular processes including immune response. Inhibition of PI3K can lead to altered immune cell activation and maturation, potentially impacting CD83 expression which is significant in immune cell functioning. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, Rapamycin affects the mTORC1 pathway, which is involved in immune cell regulation. By inhibiting mTORC1, Rapamycin may indirectly influence the expression and function of CD83, as mTOR signaling is integral to immune cell differentiation and activation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A specific inhibitor of p38 MAPK, SB203580 targets the MAPK signaling pathway. Given that MAPK pathways are involved in the regulation of immune responses, inhibition by SB203580 could indirectly modify CD83 activity, as CD83 plays a role in immune cell signaling. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor, U0126 specifically inhibits the MAPK/ERK pathway. The MAPK/ERK pathway′s role in cell proliferation and differentiation could indirectly influence CD83 expression or function in immune cells. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
As an inhibitor of JNK, SP600125 modulates the MAPK pathway. The JNK pathway's involvement in immune cell signaling and inflammatory responses suggests that its inhibition could indirectly affect CD83 activity. | ||||||
CAY10512 | 139141-12-1 | sc-205237 sc-205237A | 10 mg 100 mg | $67.00 $539.00 | ||
This inhibitor targets the NF-κB pathway, a key player in immune response regulation. By inhibiting NF-κB, the compound could indirectly modulate CD83 expression, as NF-κB is a transcription factor that regulates genes involved in immune function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A natural compound known to modulate multiple signaling pathways, including NF-κB, Akt, and MAPK. Its broad-spectrum modulation may indirectly affect CD83 activity due to the integrated nature of these signaling pathways in immune regulation. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that inhibits calcineurin, thereby impacting the NF-AT pathway. Given the role of NF-AT in immune cell activation, Cyclosporine A's action could indirectly influence CD83 expression in immune cells. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
A tyrosine kinase inhibitor, Imatinib targets BCR-ABL, c-KIT, and PDGFR. Its action on these kinases, involved in cell growth and survival, could indirectly affect CD83, particularly in the context of immune cells where these kinases play a role. | ||||||
Stat3 Inhibitor VI, S3I-201 | 501919-59-1 | sc-204304 | 10 mg | $148.00 | 104 | |
An inhibitor of STAT3, S3I-201 impacts JAK/STAT signaling, a pathway implicated in immune response regulation. By inhibiting STAT3, it may indirectly affect CD83 activity, as STAT3 can influence immune cell behavior. | ||||||