CD151 Activators belong to a chemical class of molecules that play a pivotal role in the regulation of CD151, a transmembrane protein that is part of the tetraspanin family. CD151 is a multifunctional protein found in the plasma membrane of various cell types, including blood cells, endothelial cells, and epithelial cells. It is known for its involvement in mediating cell adhesion, migration, and signal transduction. CD151 often associates with other tetraspanins and integrins, forming complexes that modulate various cellular processes. CD151 Activators are small molecules that interact with CD151, influencing its functions and contributing to the regulation of cell adhesion and signaling events.
The mechanism of action of CD151 Activators typically involves binding to specific sites on the CD151 protein, inducing conformational changes that can impact its association with other cell surface proteins, such as integrins. This alteration in protein-protein interactions can lead to changes in cell adhesion and migration properties, as well as downstream signaling pathways. CD151 Activators have garnered significant interest in cell biology research due to their ability to uncover the intricate mechanisms underlying cell adhesion and migration. By studying these molecules, researchers aim to gain insights into the fundamental processes governing cellular interactions and signaling. Understanding the role of CD151 and its regulation by CD151 Activators can provide valuable knowledge about cell behavior and function in various physiological and pathological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC), which can modulate integrin functions linked to CD151. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This polyphenol can modulate cell adhesion and migration, potentially influencing CD151-mediated processes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By elevating cAMP levels, Forskolin can influence cellular signaling pathways that might intersect with CD151. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor, which can affect cell motility and potentially impact CD151-related pathways. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
As a Src family kinase inhibitor, Dasatinib might influence CD151-associated integrin signaling. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $25.00 $75.00 $150.00 | 32 | |
This isoflavone has been shown to modulate cellular signaling pathways potentially intersecting with CD151. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $44.00 $109.00 | 61 | |
Targeting BCR-ABL, c-Kit, this could indirectly impact CD151 by modifying cell adhesion and migration. | ||||||