CatSper4 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $61.00 | 17 | |
Mifepristone could downregulate CatSper4 by blocking progesterone receptors, thus hindering the hormonal signal transduction necessary for the maintenance of CatSper4 gene transcription within sperm cells. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A may decrease CatSper4 expression by inhibiting histone deacetylases, which would result in a less condensed chromatin state around the CatSper4 gene, potentially leading to a suppression of its transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound could reduce expression of CatSper4 by inhibiting DNA methyltransferases, leading to hypomethylation of the gene's promoter region and subsequent transcriptional repression of the gene. | ||||||
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $63.00 $265.00 | 21 | |
Ketoconazole may inhibit CatSper4 expression by impairing steroid synthesis, specifically reducing the levels of hormones that are crucial for the transcriptional activation of the CatSper4 gene. | ||||||
Flutamide | 13311-84-7 | sc-204757 sc-204757A sc-204757D sc-204757B sc-204757C | 1 g 5 g 25 g 500 g 1 kg | $47.00 $156.00 $171.00 $525.00 $941.00 | 4 | |
Flutamide has the potential to decrease CatSper4 expression by competitively binding to androgen receptors, thereby obstructing the androgenic stimulation necessary for the gene's expression in spermatozoa. | ||||||
Fenvalerate | 51630-58-1 | sc-24014 sc-24014A | 25 mg 100 mg | $80.00 $231.00 | 2 | |
Fenvalerate could downregulate CatSper4 through neurotoxic effects that alter intracellular signaling pathways, potentially leading to a decrease in the transcriptional activity of the gene encoding for the CatSper4 protein. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Cadmium chloride may reduce the expression of CatSper4 by inducing oxidative stress, which can trigger a cascade of cellular events culminating in the repression of transcription for certain calcium channel-related genes. | ||||||
Lead(II) Acetate | 301-04-2 | sc-507473 | 5 g | $85.00 | ||
Lead acetate could inhibit the expression of CatSper4 by causing epigenetic changes that lead to the silencing of the gene or by interfering with the binding of transcription factors to the gene's promoter region. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin might decrease CatSper4 expression by disrupting the endoplasmic reticulum calcium gradient, which is a critical secondary messenger in the signaling pathways that govern the transcription of many genes, including CatSper4. | ||||||
Vinclozolin | 50471-44-8 | sc-251425 | 250 mg | $23.00 | 1 | |
Vinclozolin could inhibit the expression of CatSper4 by acting as an antagonist to androgen receptors, which play a role in the transcriptional regulation of genes involved in spermatogenesis and sperm function. | ||||||