Date published: 2025-11-26

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CaSR Antibodies

Santa Cruz Biotechnology provides a broad selection of CaSR monoclonal antibodies for investigating the calcium-sensing receptor's role in various physiological processes. CaSR monoclonal antibodies are compatible with western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).The calcium-sensing receptor (CaSR) is a critical component in maintaining calcium homeostasis and plays a significant role in regulating parathyroid hormone secretion, renal calcium reabsorption, and bone metabolism. Dysregulation of CaSR has been implicated in various disorders, including hyperparathyroidism and osteoporosis, making it an important target for therapeutic intervention. Research focused on CaSR can provide insights into these conditions and aid in the development of new treatment strategies. CaSR monoclonal antibodies enable researchers to explore calcium signaling pathways and their effects on cellular function. Understanding CaSR activity and regulation contributes to knowledge about calcium-related disorders and potential therapeutic approaches. Investigating CaSR expression patterns helps reveal its distribution across different tissues and cell types. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of calcium homeostasis and related pathologies.

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CaSR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CaSR Antibody (6D4)

sc-47741mouse IgG1 κ15-29 (r)WB, IP, IFm, r, h and rabbit
21
(5)

CaSR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CaSR CRISPR/Cas9 KO Plasmid (h2)

sc-401749-KO-2hGene KnockoutGFP
1
(0)

CaSR HDR Plasmid (h2)

sc-401749-HDR-2hHomology Directed RepairPuromycin
1
(0)

CaSR Double Nickase Plasmid (h)

sc-401749-NIChGene KnockoutPuromycin
1
(0)

CaSR Double Nickase Plasmid (h2)

sc-401749-NIC-2hGene KnockoutPuromycin
1
(0)

CaSR CRISPR/Cas9 KO Plasmid (m)

sc-419473mGene KnockoutGFP0
(0)

CaSR HDR Plasmid (m)

sc-419473-HDRmHomology Directed RepairPuromycin0
(0)

CaSR Double Nickase Plasmid (m)

sc-419473-NICmGene KnockoutPuromycin0
(0)

CaSR Double Nickase Plasmid (m2)

sc-419473-NIC-2mGene KnockoutPuromycin0
(0)

CaSR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CaSR CRISPR Activation Plasmid (h)

sc-401749-ACThGene ActivationPuro, Blast, Hygro
1
(0)

CaSR CRISPR Activation Plasmid (h2)

sc-401749-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

CaSR Lentiviral Activation Particles (h)

sc-401749-LAChGene ActivationPuro, Blast, Hygro
1
(0)

CaSR Lentiviral Activation Particles (h2)

sc-401749-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

CaSR CRISPR Activation Plasmid (m)

sc-419473-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CaSR CRISPR Activation Plasmid (m2)

sc-419473-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CaSR Lentiviral Activation Particles (m)

sc-419473-LACmGene ActivationPuro, Blast, Hygro0
(0)

CaSR Lentiviral Activation Particles (m2)

sc-419473-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CaSR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CaSR siRNA (h)

sc-44373hGene SilencingN/A
14
(0)

CaSR shRNA Plasmid (h)

sc-44373-SHhGene SilencingPuromycin
14
(0)

CaSR shRNA (h) Lentiviral Particles

sc-44373-VhGene SilencingPuromycin
14
(0)

CaSR siRNA (m)

sc-44374mGene SilencingN/A
1
(0)

CaSR shRNA Plasmid (m)

sc-44374-SHmGene SilencingPuromycin
1
(0)

CaSR shRNA (m) Lentiviral Particles

sc-44374-VmGene SilencingPuromycin
1
(0)

CaSR siRNA (r)

sc-270329rGene SilencingN/A
2
(0)

CaSR shRNA Plasmid (r)

sc-270329-SHrGene SilencingPuromycin
2
(0)

CaSR shRNA (r) Lentiviral Particles

sc-270329-VrGene SilencingPuromycin
2
(0)