CAS Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Sorafenib is a multikinase inhibitor that targets RAF/MEK/ERK signaling pathways. By inhibiting these pathways, Sorafenib indirectly influences cellular processes related to CAS, as CAS is intricately involved in signal transduction cascades activated by these kinases. The compound's impact on MAPK signaling, including the downregulation of ERK, can affect CAS modulation, making Sorafenib a potential indirect inhibitor of CAS-mediated cellular functions. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib is a tyrosine kinase inhibitor with activity against SRC family kinases. CAS is known to interact with SRC and participate in downstream signaling. Inhibition of SRC by Dasatinib can disrupt the pathways where CAS is involved, thereby indirectly modulating CAS-mediated cellular processes. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is a selective inhibitor of SRC family kinases, including SRC itself. Since CAS interacts with and is regulated by SRC, the inhibition of SRC by PP2 can impact CAS-mediated cellular processes. Understanding the consequences of SRC inhibition on CAS function provides insights into the regulatory mechanisms governing CAS activity in the context of tyrosine kinase signaling. | ||||||
A 419259 trihydrochloride | 1435934-25-0 | sc-361094 | 5 mg | $209.00 | 6 | |
A-419259 is a potent and selective inhibitor of FAK (focal adhesion kinase), a protein closely linked to CAS in cellular adhesion and migration. Inhibiting FAK with A-419259 can disrupt the focal adhesion dynamics where CAS plays a role, indirectly affecting CAS-mediated cellular functions. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Blebbistatin is a myosin II inhibitor that indirectly influences CAS-mediated cellular processes by disrupting actomyosin contractility. CAS is involved in the regulation of actomyosin dynamics, and inhibiting myosin II with Blebbistatin can impact these processes. Exploring the interplay between Blebbistatin and CAS provides valuable insights into the connections between cytoskeletal dynamics and CAS function in the context of cell motility and migration. | ||||||
FAK Inhibitor 14 | 4506-66-5 | sc-203950 sc-203950A | 10 mg 50 mg | $107.00 $233.00 | 86 | |
FAK Inhibitor 14 is a selective inhibitor of focal adhesion kinase (FAK). Since CAS is closely associated with FAK in cellular adhesion and migration, inhibiting FAK with FAK Inhibitor 14 can disrupt the signaling pathways where CAS is involved, indirectly modulating CAS-mediated cellular functions. | ||||||
EHop-016 | 1380432-32-5 | sc-497382 | 5 mg | $78.00 | ||
EHop-016 is a small molecule inhibitor that specifically targets Rac1. CAS interacts with and is regulated by Rac1, particularly in the context of cell motility and migration. Inhibiting Rac1 with EHop-016 can disrupt the pathways where CAS is involved, indirectly affecting CAS-mediated cellular functions. | ||||||
RKI-1447 | 1342278-01-6 | sc-472590 | 1 mg | $330.00 | ||
RKI-1447 is a selective inhibitor of ROCK, a regulator of the actomyosin cytoskeleton. CAS is involved in actomyosin dynamics, and inhibiting ROCK with RKI-1447 can impact these processes, indirectly influencing CAS-mediated cellular functions. Exploring the interplay between RKI-1447 and CAS provides valuable insights into the connections between cytoskeletal dynamics and CAS function in the context of cell motility and migration. | ||||||