Carnitine Acetyltransferase Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
rac- Etomoxir | 82258-36-4 | sc-208284 | 20 mg | $580.00 | 1 | |
Rac-Etomoxir acts as a potent inhibitor of carnitine acetyltransferase, disrupting fatty acid metabolism by modulating substrate binding dynamics. Its unique structure allows for specific interactions with the enzyme's active site, leading to altered reaction kinetics. The compound's hydrophobic regions facilitate enhanced binding affinity, while its stereochemistry influences the orientation of substrate molecules, ultimately affecting metabolic pathways and energy production. | ||||||
(R)-Amino Carnitine | 98063-21-9 | sc-208234 | 5 mg | $316.00 | ||
(R)-Amino Carnitine serves as a substrate for carnitine acetyltransferase, participating in the transfer of acyl groups within metabolic pathways. Its chiral configuration enhances specificity in enzyme interactions, promoting efficient substrate conversion. The compound's unique functional groups facilitate hydrogen bonding and electrostatic interactions, optimizing binding affinity. Additionally, its role in modulating the enzyme's conformational dynamics influences reaction rates, impacting overall metabolic efficiency. | ||||||
(+)-Etomoxir sodium salt | 828934-41-4 | sc-215009 sc-215009A | 5 mg 25 mg | $148.00 $496.00 | 3 | |
Inhibits carnitine palmitoyltransferase 1 (CPT1), blocking fatty acid entry into mitochondria for β-oxidation. | ||||||
2-Bromooctadecanoic acid | 142-94-9 | sc-256100 sc-256100A | 1 g 2 g | $129.00 $200.00 | ||
2-Bromooctadecanoic acid acts as an inhibitor of carnitine acetyltransferase, disrupting acyl group transfer in metabolic processes. The presence of the bromine atom introduces steric hindrance, altering enzyme-substrate interactions and potentially affecting reaction kinetics. Its long hydrocarbon chain enhances hydrophobic interactions, influencing membrane permeability and enzyme accessibility. This compound's unique structure can modulate enzyme activity, impacting metabolic flux in lipid metabolism pathways. | ||||||
rac Perhexiline Maleate | 6724-53-4 | sc-460183 | 10 mg | $184.00 | ||
Inhibits CPT1, reducing mitochondrial fatty acid uptake and promoting glucose utilization. | ||||||
(S)-Amino Carnitine | 125377-87-9 | sc-391837 | 2.5 mg | $430.00 | ||
(S)-Amino Carnitine serves as a substrate for carnitine acetyltransferase, facilitating the transfer of acetyl groups in metabolic pathways. Its chiral amino group enhances specificity in enzyme interactions, promoting efficient substrate binding. The compound's unique stereochemistry influences the orientation of acyl group transfer, potentially affecting reaction rates. Additionally, its polar characteristics may enhance solubility in biological systems, impacting cellular uptake and distribution. | ||||||
1-(2,3,4-Trimethoxybenzyl)piperazine | 5011-34-7 | sc-297236 | 500 mg | $367.00 | ||
Shifts energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting CPT1. | ||||||
Ranolazine | 95635-55-5 | sc-212769 | 1 g | $107.00 | 3 | |
Reduces fatty acid oxidation by inhibiting CPT1, improving myocardial oxygen utilization. | ||||||
Ivabradine Hydrochloride | 148849-67-6 | sc-211682 | 10 mg | $250.00 | 2 | |
Slows heart rate by inhibiting the funny current (If) in the sinoatrial node, indirectly affecting fatty acid oxidation. | ||||||
Meldonium | 76144-81-5 | sc-207887 | 100 mg | $252.00 | 1 | |
May inhibit CPT1 and modulate fatty acid oxidation, potentially enhancing glucose utilization. | ||||||