Date published: 2025-10-15

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Calpastatin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Calpastatin monoclonal antibodies for research focused on understanding the regulation of calpain activity. Calpastatin monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Calpastatin is a crucial inhibitor of calpain, a family of calcium-dependent cysteine proteases involved in numerous cellular processes, including apoptosis, cell motility, and cytoskeletal remodeling. By regulating calpain activity, Calpastatin plays a significant role in maintaining cellular homeostasis and modulating signal transduction pathways. Understanding the function of Calpastatin is essential for elucidating its impact on various physiological and pathological conditions. Calpastatin research has revealed important connections to neurodegenerative disorders, cardiovascular diseases, and cancer progression. Investigating Calpastatin's regulatory mechanisms can provide new perspectives on potential therapeutic strategies. Current research explores how Calpastatin influences cellular responses to stress and injury. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of Calpastatin's role in health and disease.

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Calpastatin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Calpastatin Antibody (PI-11)

sc-32324mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
5
(3)

Calpastatin Antibody (A-1)

sc-376547mouse IgG1 κ409-708 (h)WB, IP, IF, IHC(P), ELISAh
3
(4)

Calpastatin Antibody (2Q31)

sc-70486mouse IgG1 κ(h)WB, IP, IFm, r, h

new

(2)

Calpastatin Antibody (PI-9)

sc-81172mouse IgG1(h)WB, IFh

new

(1)

Calpastatin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Calpastatin CRISPR/Cas9 KO Plasmid (h)

sc-401502hGene KnockoutGFP0
(0)

Calpastatin HDR Plasmid (h)

sc-401502-HDRhHomology Directed RepairPuromycin0
(0)

Calpastatin Double Nickase Plasmid (h)

sc-401502-NIChGene KnockoutPuromycin0
(0)

Calpastatin Double Nickase Plasmid (h2)

sc-401502-NIC-2hGene KnockoutPuromycin0
(0)

Calpastatin CRISPR/Cas9 KO Plasmid (m)

sc-419474mGene KnockoutGFP0
(0)

Calpastatin HDR Plasmid (m)

sc-419474-HDRmHomology Directed RepairPuromycin0
(0)

Calpastatin Double Nickase Plasmid (m)

sc-419474-NICmGene KnockoutPuromycin0
(0)

Calpastatin Double Nickase Plasmid (m2)

sc-419474-NIC-2mGene KnockoutPuromycin0
(0)

Calpastatin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Calpastatin CRISPR Activation Plasmid (h)

sc-401502-ACThGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin CRISPR Activation Plasmid (h2)

sc-401502-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin Lentiviral Activation Particles (h)

sc-401502-LAChGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin Lentiviral Activation Particles (h2)

sc-401502-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin CRISPR Activation Plasmid (m)

sc-419474-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin CRISPR Activation Plasmid (m2)

sc-419474-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin Lentiviral Activation Particles (m)

sc-419474-LACmGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin Lentiviral Activation Particles (m2)

sc-419474-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Calpastatin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Calpastatin siRNA (h)

sc-29889hGene SilencingN/A
1
(0)

Calpastatin shRNA Plasmid (h)

sc-29889-SHhGene SilencingPuromycin
1
(0)

Calpastatin shRNA (h) Lentiviral Particles

sc-29889-VhGene SilencingPuromycin
1
(0)

Calpastatin siRNA (m)

sc-29890mGene SilencingN/A0
(0)

Calpastatin shRNA Plasmid (m)

sc-29890-SHmGene SilencingPuromycin0
(0)

Calpastatin shRNA (m) Lentiviral Particles

sc-29890-VmGene SilencingPuromycin0
(0)