Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
A SERCA pump inhibitor that leads to increased intracellular calcium levels. As Calpain 13 requires calcium for activation, the elevation of intracellular calcium by Thapsigargin can enhance Calpain 13 activity by providing the necessary ions for its catalytic activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Calcium ionophore that increases intracellular calcium by facilitating the influx of extracellular calcium. This increase in intracellular calcium concentration can enhance the activity of Calpain 13 by providing the calcium ions needed for its enzymatic function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A known stimulator of calcium release from intracellular stores. It can enhance Calpain 13 activity by increasing cytosolic calcium concentration, thereby indirectly contributing to the activation state of Calpain 13. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
A cholinergic agonist that can cause the release of calcium from intracellular stores, thereby potentially enhancing the activation of Calpain 13 by increasing the intracellular calcium levels. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $223.00 $799.00 | 19 | |
Targets ryanodine receptors to induce release of calcium from the sarcoplasmic and endoplasmic reticulum. By increasing intracellular calcium, Ryanodine can indirectly enhance the activity of Calpain 13. | ||||||
Cyclopiazonic Acid | 18172-33-3 | sc-201510 sc-201510A | 10 mg 50 mg | $176.00 $624.00 | 3 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA), leading to increased cytosolic calcium levels. Elevated calcium can enhance Calpain 13 activity as calpains are calcium-dependent proteases. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
A calcium channel blocker that can lead to the activation of compensatory mechanisms to increase intracellular calcium, potentially enhancing Calpain 13 activity by indirectly increasing the level of calcium ions available for Calpain 13 activation. | ||||||
Nicardipine hydrochloride | 54527-84-3 | sc-202731 sc-202731A | 1 g 5 g | $33.00 $83.00 | 5 | |
Another calcium channel blocker that may trigger homeostatic responses resulting in increased intracellular calcium, which can enhance the activity of Calpain 13 by providing more calcium ions necessary for its activation. | ||||||
FPL-64176 | 120934-96-5 | sc-201491 | 5 mg | $83.00 | 1 | |
A calcium channel activator that can increase intracellular calcium concentration, indirectly enhancing Calpain 13 activity by increasing the availability of calcium ions. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $84.00 $196.00 $817.00 | ||
An L-type calcium channel agonist that can increase intracellular calcium, thereby potentially enhancing the functional activity of Calpain 13 through increased availability of calcium ions for its activation. | ||||||