Calcium Indicators

CalciFluor™ Fluo-8H, sodium salt, exhibits remarkable selectivity for calcium ions, enabling precise detection through its unique chelation mechanism. This compound undergoes distinct conformational changes upon calcium binding, resulting in a significant increase in fluorescence intensity. Its kinetic profile allows for swift interactions, making it ideal for tracking calcium signaling pathways. Additionally, its high aqueous solubility enhances its compatibility with various experimental conditions, ensuring reliable performance in diverse applications.

Coelenterazine-h is a luminescent compound that exhibits unique interactions with calcium ions, facilitating bioluminescence in various biological systems. Upon binding to calcium, it undergoes a conformational shift that enhances its light-emitting properties. This compound's reaction kinetics are characterized by rapid luminescent responses, making it suitable for real-time monitoring of calcium dynamics. Its stability in aqueous environments further supports its utility in diverse experimental setups.

CA 1001 is a calcium-based compound that demonstrates remarkable reactivity with various anions, leading to the formation of stable complexes. Its unique coordination chemistry allows for selective binding, influencing ion transport mechanisms. The compound exhibits distinct solubility characteristics, enhancing its interaction with biological membranes. Additionally, CA 1001's kinetic profile reveals a rapid equilibrium in solution, facilitating dynamic exchanges that are crucial for cellular processes.

Quin II is a calcium compound characterized by its ability to form transient complexes with ligands, showcasing unique chelation properties. Its interaction with metal ions is marked by specific coordination geometries, which can alter the electronic environment and influence reaction rates. The compound's solubility in polar solvents enhances its mobility, while its reactivity profile indicates a propensity for rapid ligand exchange, making it a key player in various biochemical pathways.

INDO 1/AM is a calcium-sensitive fluorescent probe that exhibits remarkable selectivity for calcium ions through a unique conformational change upon binding. This change alters its fluorescence properties, enabling real-time monitoring of calcium dynamics in cellular environments. The probe's high affinity for calcium facilitates rapid binding kinetics, while its hydrophobic characteristics enhance membrane permeability, allowing for effective intracellular localization and signaling studies.

5,5'-Difluoro BAPTA (AM) is a potent calcium chelator that selectively binds calcium ions, leading to a significant alteration in its fluorescence characteristics. This compound features a unique structure that promotes rapid interaction with calcium, resulting in swift kinetics that enhance its effectiveness in dynamic environments. Its lipophilic nature allows for efficient cellular uptake, making it an ideal candidate for probing calcium signaling pathways and intracellular calcium fluctuations.

BAPTA-APM is a highly selective calcium chelator known for its ability to form stable complexes with calcium ions, effectively modulating calcium homeostasis. Its unique design facilitates specific interactions with calcium, influencing various signaling pathways. The compound exhibits distinct fluorescence properties upon binding, allowing for real-time monitoring of calcium dynamics. Additionally, its solubility profile enhances its distribution in biological systems, making it suitable for studying calcium-mediated processes.

CalciFluor™ Fluo-8, pentapotassium salt, is a potent calcium indicator characterized by its exceptional affinity for calcium ions, enabling precise detection and quantification. Its unique structure promotes rapid binding kinetics, facilitating swift responses to calcium fluctuations. The compound exhibits remarkable fluorescence enhancement upon calcium binding, providing high sensitivity for imaging applications. Its stability in diverse environments ensures reliable performance in various experimental conditions, making it a valuable tool for exploring calcium signaling dynamics.

CalciFluor™ Rhod-4, AM is a specialized calcium indicator that showcases unique photophysical properties, including a significant increase in fluorescence intensity upon calcium ion interaction. This compound features a lipophilic structure that enhances cellular permeability, allowing for effective intracellular calcium monitoring. Its rapid response time to calcium fluctuations and distinct spectral characteristics make it ideal for real-time imaging, providing insights into calcium-mediated processes with high spatial resolution.

CalciFluor™ Fluo-8FF, AM is an advanced calcium indicator characterized by its exceptional sensitivity to calcium ion concentrations. This compound exhibits a remarkable fluorescence enhancement upon binding to calcium, enabling precise detection of dynamic calcium signaling events. Its unique design incorporates a hydrophobic moiety that facilitates membrane penetration, ensuring effective localization within cellular compartments. The rapid kinetics of its fluorescence response allows for real-time monitoring of calcium transients, making it a powerful tool for studying calcium-dependent cellular processes.