CaBP3 inhibitors, also known as Calcium-Binding Protein 3 inhibitors, represent a class of small molecules that have garnered considerable attention in the field of molecular biology and cellular research. These inhibitors are designed to selectively target and modulate the activity of CaBP3, a calcium-binding protein that plays a pivotal role in various cellular processes. CaBP3 itself is involved in calcium signaling, acting as a calcium sensor and regulating calcium-dependent events within the cell. Consequently, the development of inhibitors that can specifically interact with CaBP3 has opened new avenues for understanding the intricate mechanisms of calcium signaling and its impact on cellular function.
The mechanism of action of CaBP3 inhibitors primarily centers on disrupting or modulating the calcium-binding properties of CaBP3. These inhibitors are engineered to bind to specific regions or domains of CaBP3, thereby inhibiting its interaction with calcium ions. By doing so, they effectively alter the protein's conformational structure or its ability to relay calcium signals, leading to downstream effects on cellular processes that depend on calcium signaling. Researchers have been particularly interested in CaBP3 inhibitors due to their dissect the roles of calcium signaling in cell differentiation, proliferation, and apoptosis. Through the selective inhibition of CaBP3, scientists aim to unravel the precise contributions of this protein in various cellular contexts, shedding light on fundamental biological processes and identifying novel molecular targets for further research. CaBP3 inhibitors thus represent valuable tools in the realm of cellular and molecular biology, enabling a deeper understanding of calcium signaling pathways and their implications in diverse biological systems.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin suppresses CBP/p300-mediated transcription by disrupting their interaction with various transcription factors. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
C646 is a selective inhibitor of the interaction between p300/CBP and the transcription factor p53, inhibiting p53 acetylation. | ||||||
A-485 | 1889279-16-6 | sc-507493 | 5 mg | $275.00 | ||
A-485 is a potent and selective inhibitor of both CBP and p300 histone acetyltransferases, modulating gene transcription. | ||||||
SGC-CBP30 | 1613695-14-9 | sc-473871 sc-473871A | 5 mg 10 mg | $178.00 $338.00 | ||
SGC-CBP30 selectively inhibits the interaction of CBP with β-catenin, preventing β-catenin-driven transcriptional activation. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
Garcinol inhibits p300/CBP acetyltransferase activity, affecting histone acetylation and gene transcription. | ||||||