Date published: 2025-10-27

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C2orf50 Inhibitors

Staurosporine is a broad-spectrum kinase inhibitor that can suppress the activity of a wide array of kinases; if C2orf50 has kinase activity or interacts with kinases, Staurosporine can affect its function. LY294002 and PD98059 target key components within the PI3K/Akt and MAPK/ERK pathways, respectively, which are central to regulating cell survival, proliferation, and differentiation. Rapamycin is well-known for its role in inhibiting mTOR, which can control cell growth and may intersect with C2orf50's function. Cyclopamine and SB431542 inhibit the Hedgehog and TGF-β signaling pathways, respectively, which could be relevant if C2orf50 plays a role in these pathways.

Bortezomib and MG132 are proteasome inhibitors that could stabilize proteins by preventing their degradation, potentially impacting the turnover of C2orf50 if it is rapidly degraded under normal conditions. Epigenetic modifiers such as 5-Azacytidine and Trichostatin A can alter gene expression and chromatin structure, which may affect the expression level or function of C2orf50. Y-27632, a ROCK inhibitor, can influence the cytoskeleton organization, and if C2orf50 is involved in this process, its function could be impacted.

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