C23 Activators
C23 activators are a designation for a class of chemical compounds that are characterized by their ability to modulate the activity of a specific cellular pathway or process. The "C23" in their name typically stands for a particular target or mechanism within the cell that these molecules are designed to interact with, though without the context of a specific biochemical pathway or target, the term remains somewhat abstract. These activators function at the molecular level, often by binding to their target site and altering its conformation or activity. This binding can lead to an increase in the activity of certain proteins, enzymes, or receptors, thereby amplifying the natural processes within the cell that are associated with the C23 function.
The specificity of C23 activators lies in their molecular structure, which is crafted to fit neatly into their target site, much like a key fits into a lock. The design of such molecules is a sophisticated process that involves a deep understanding of molecular biology, chemistry, and the intricate dance of interactions within the cell. These activators may be small organic molecules or could be larger biological molecules, such as peptides or modified nucleic acids.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK. Activation of C23 is enhanced through the p38 MAPK pathway. SB203580 inhibits p38 MAPK, preventing its negative regulation on C23 and leading to enhanced functional activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. C23 is associated with the JNK pathway. Inhibition of JNK by SP600125 leads to the alleviation of negative regulation on C23, resulting in increased functional activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor. Similar to LY294002, Wortmannin enhances C23 activity by inhibiting PI3K and subsequently preventing its negative regulation on C23 through the PI3K/AKT pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor targeting the MAPK/ERK pathway. By inhibiting MEK, PD98059 enhances the activation of C23, which is involved in the MAPK/ERK signaling cascade. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 is a TGF-β receptor inhibitor. C23 is implicated in TGF-β signaling. Inhibition of TGF-β receptor by SB431542 releases C23 from negative regulation within the TGF-β pathway, leading to increased functional activity. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $265.00 | ||
LY3214996 is a potent and selective TGF-β receptor type 1 (TGFBR1) inhibitor. By blocking TGFBR1, LY3214996 enhances the functional activity of C23 by relieving its negative regulation within the TGF-β signaling pathway. | ||||||
SP2509 | 1423715-09-6 | sc-492604 | 5 mg | $284.00 | ||
SP2509 is a histone deacetylase (HDAC) inhibitor. C23 function is influenced by HDACs. SP2509 enhances C23 activity by inhibiting HDACs, leading to increased acetylation levels and subsequent activation of C23. | ||||||
A-443654 | 552325-16-3 | sc-507339 | 1 mg | $140.00 | ||
A443654 is a pan-Akt inhibitor. C23 is involved in the PI3K/AKT pathway. Inhibition of Akt by A443654 enhances the functional activity of C23 by preventing its negative regulation within the PI3K/AKT signaling cascade. | ||||||
AZD5363 | 1143532-39-1 | sc-503190 | 5 mg | $309.00 | ||
AZD5363 is a pan-Akt kinase inhibitor. Similar to A443654, AZD5363 enhances C23 activity by inhibiting Akt, preventing its negative regulation on C23 within the PI3K/AKT signaling pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 is an inhibitor of NF-κB. C23 is implicated in the NF-κB pathway. Inhibition of NF-κB by BAY 11-7082 enhances the functional activity of C23 by alleviating its negative regulation within the NF-κB signaling cascade. | ||||||