C20orf135 Inhibitors
The approach to inhibiting C20orf135 is primarily indirect due to the limited knowledge regarding the specific functions and pathways associated with this protein. Chemicals such as Staurosporine, LY294002, and Rapamycin target a wide range of pathways, from kinase activity and the PI3K pathway to the mTOR pathway. By modulating these pathways, they can influence the activity or expression of a myriad of downstream targets, which may include C20orf135. Agents like MG132 and Cycloheximide, which inhibit protein degradation and synthesis, respectively, provide a broad method to impact protein function and stability, influencing proteins of unknown or under-studied functions.
Similarly, inhibitors like Nocodazole and Calyculin A, which affect cell cycle progression and phosphorylation status, offer a broad strategy to influence the cellular environment. Such agents can modulate the activity, localization, or stability of a variety of proteins, even those with less-defined roles like C20orf135. With the current understanding, targeting C20orf135 specifically remains challenging. Therefore, a broader, pathway-centric approach provides an avenue to indirectly modulate its function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
General kinase inhibitor. By broadly inhibiting kinase activity, it might indirectly alter C20orf135 if it relies on phosphorylation events for its function or stability. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor. If C20orf135 operates within or downstream of the PI3K pathway, this inhibitor might indirectly modulate its activity or expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor. If C20orf135 is involved in processes regulated by mTOR, such as protein synthesis or autophagy, Rapamycin can indirectly influence its function. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor. If C20orf135 undergoes proteasomal degradation, MG132 can enhance its stability and prolong its cellular presence. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Microtubule depolymerizing agent. If C20orf135 is involved in cell cycle events or relies on microtubule dynamics, Nocodazole might indirectly affect its function. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Protein synthesis inhibitor. If C20orf135 has a short half-life or its synthesis is triggered by specific stimuli, Cycloheximide can indirectly prevent its accumulation. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
PP1 and PP2A phosphatase inhibitor. If C20orf135's activity or function is regulated by dephosphorylation events, Calyculin A might impact it indirectly. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor. If C20orf135 is in any way associated with the MAPK signaling cascade, PD98059 can affect its function or expression indirectly. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor. Like LY294002, if C20orf135's function or expression relies on the PI3K-Akt pathway, Wortmannin can modulate it indirectly. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Glucose analog inhibiting glycolysis. If C20orf135 has roles in metabolism or cellular energy processes, its function might be indirectly altered by this compound. | ||||||