Actin-like protein 10 (ACTL10) is a relatively uncharacterized member of the actin family of proteins. Actins are highly conserved proteins that play a fundamental role in the formation of the cytoskeleton and are involved in various types of cell motility, structure, and integrity. ACTL10 shares homology with conventional actins but has specific features that differentiate it from the muscle and non-muscle actin isoforms.ACTL10 is thought to perform specialized functions within the cell, possibly associated with the dynamic remodeling of the cytoskeleton. Its expression patterns and protein interactions suggest it may be involved in processes that are distinct from those carried out by the classical actins. Like other actins, ACTL10 is presumed to have the ability to polymerize into filaments, which are essential components of the cytoskeleton.
The cytoskeleton is a dynamic network that gives the cell its shape and capacity for movement and is crucial for a wide range of cellular operations, including division, signaling, and material transport. The actin filaments, also known as microfilaments, are the thinnest filaments of the cytoskeleton and are primarily composed of polymerized actin. ACTL10 may contribute to the formation of these structures or participate in the regulation of their assembly and disassembly.In-depth studies of ACTL10 are needed to clarify its role and regulation. Detailed knowledge about the function of actin-like proteins can provide insights into their contribution to cellular architecture and pathology. Abnormalities in actin dynamics and filament organization are implicated in a variety of diseases, including muscular disorders, cardiomyopathies, and cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D disrupts actin filament polymerization and could indirectly influence ACTL10 by altering actin dynamics. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide stabilizes actin filaments and may affect ACTL10 through its influence on actin polymerization. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A binds to actin monomers, preventing their polymerization, and might indirectly impact ACTL10. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Phalloidin binds and stabilizes actin filaments, potentially influencing ACTL10 through effects on cytoskeletal dynamics. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632, a ROCK inhibitor, affects actin cytoskeleton remodeling and could indirectly impact ACTL10. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Blebbistatin inhibits myosin II, and its effects on actin-myosin interaction might indirectly influence ACTL10. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule dynamics and, through changes in cellular architecture, might affect ACTL10. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and, by altering cytoskeletal dynamics, may indirectly affect ACTL10. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
ML-7 is an inhibitor of myosin light chain kinase (MLCK), potentially influencing ACTL10 through actin-myosin regulation. | ||||||