TMEM240 inhibitors belong to a class of chemical compounds specifically designed to target and modulate the activity of the TMEM240 protein, also known as Transmembrane Protein 240. TMEM240 is a relatively less characterized protein, and its precise functions within cells are still a subject of ongoing research. It is a transmembrane protein, indicating that it spans the cell membrane, and its cellular localization suggests potential roles in membrane-related processes. Inhibitors designed to target TMEM240 are primarily employed in molecular and cellular biology research to investigate the functional properties and regulatory mechanisms associated with this protein.
The development of TMEM240 inhibitors typically involves a combination of biochemical, biophysical, and structural approaches aimed at identifying or designing molecules that can selectively interact with TMEM240 and modulate its activity within the cellular context. While the exact functions of TMEM240 are not fully elucidated, researchers use these inhibitors to explore its roles in various cellular processes. These investigations aim to uncover the protein's contributions to cell biology, such as membrane dynamics, intracellular signaling, and potential interactions with other cellular components. Furthermore, TMEM240 inhibitors serve as valuable tools for deciphering the broader network of cellular pathways involving this protein, contributing to our understanding of fundamental cell biology mechanisms and providing insights into potential avenues for further scientific exploration.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin binds to the beta subunit of RNA polymerase, potentially reducing the transcription of various genes, which could include TMEM240. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, and its activity could lead to a decrease in mRNA synthesis across many genes, potentially affecting TMEM240 levels. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and could reduce TMEM240 mRNA synthesis and consequently its protein levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is known to inhibit the transcription of various genes by affecting RNA polymerase II activity, which could reduce TMEM240 expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II transcriptional elongation, potentially decreasing TMEM240 expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin (3'-deoxyadenosine) can terminate mRNA chain elongation, potentially leading to decreased expression of TMEM240. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during protein synthesis, possibly affecting the overall levels of TMEM240. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin interferes with peptide chain elongation on ribosomes, potentially reducing the synthesis of proteins like TMEM240. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis, potentially decreasing the production of various proteins, including TMEM240. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine inhibits the initial elongation step of protein synthesis, which could result in reduced levels of TMEM240 protein. | ||||||