C1orf187 Inhibitors
The "Dorsal Inhibitory Axon Guidance Protein," as its name suggests, is likely involved in the intricate process of axon guidance, a critical aspect of neural development and connectivity. Axon guidance is the mechanism by which neurons send out their axons-long, threadlike extensions used to transmit electrical signals-to reach the correct targets and establish functional neural circuits.
Proteins involved in axon guidance can act through a variety of mechanisms, such as serving as ligands for receptors on the growth cone-the dynamic tip of a growing axon-or as components of the extracellular matrix that provide structural pathways or boundaries for growth cones to follow. An inhibitory guidance protein might bind to axonal receptors, triggering intracellular signaling pathways that cause the growth cone to retract or steer away from certain areas. Alternatively, it could create a barrier or gradient in the extracellular environment that deters axons from entering specific regions.Understanding the function of the "Dorsal Inhibitory Axon Guidance Protein" is fundamental for insights into how the nervous system forms and maintains its complex wiring diagram.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $151.00 $609.00 | 75 | |
A Rac1 inhibitor, NSC23766 disrupts Rac1 activation, which is crucial for cytoskeletal reorganization in neurons, potentially influencing DIAGP-mediated axon guidance. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that can affect various signaling pathways involved in neural development and axon guidance, possibly impacting DIAGP's function indirectly. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule polymerization, affecting axon guidance and neuronal morphology, which could indirectly modify DIAGP's role in neural pathways. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
By stabilizing microtubules, paclitaxel affects cell structure and intracellular transport in neurons, potentially influencing DIAGP-related axon guidance processes. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, Y-27632 can modulate cytoskeletal organization and cell migration, which may indirectly affect DIAGP's function in axon guidance. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
This compound inhibits p38 MAPK, involved in inflammatory responses and neural development, potentially altering DIAGP-associated pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
A MEK inhibitor, U0126 may indirectly influence DIAGP activity by blocking the MAPK/ERK pathway, important in neural differentiation and axon guidance. | ||||||
Wnt-C59 | 1243243-89-1 | sc-475634 sc-475634A sc-475634B | 5 mg 10 mg 50 mg | $214.00 $326.00 $1275.00 | 1 | |
Wnt-C59 inhibits Wnt signaling, a pathway involved in neural development and axon guidance, potentially affecting DIAGP-mediated processes. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
A γ-secretase inhibitor, DAPT blocks Notch signaling, which plays a crucial role in neural development and could indirectly modulate DIAGP's function in axon guidance. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
By inhibiting the Hedgehog signaling pathway, cyclopamine affects cell fate determination and axon guidance, potentially impacting DIAGP-related mechanisms. | ||||||