C14orf109 inhibitors constitute a specialized class of chemical compounds designed to selectively modulate the activity of the Chromosome 14 Open Reading Frame 109 (C14orf109) protein. This open reading frame remains relatively uncharacterized in terms of its molecular functions and cellular roles. The inhibitors developed for C14orf109 exhibit a specific chemical structure enabling them to interact selectively with defined binding sites on the C14orf109 protein, thereby influencing its molecular activities at the cellular level. The careful design of these inhibitors is essential for ensuring a high degree of specificity, minimizing unintended effects on other cellular components or proteins within the broader open reading frame family.
The mechanism of action of C14orf109 inhibitors involves disrupting the normal functioning of the C14orf109 protein, potentially impacting cellular processes associated with its functional role. As an open reading frame, C14orf109 represents a genomic region that may encode a functional protein, although the exact nature of its contributions to cellular physiology remains to be fully elucidated. The selectivity of these inhibitors is crucial to prevent interference with other closely related open reading frames or cellular pathways. As researchers explore the complexities of functional genomics and the role of lesser-known open reading frames, C14orf109 inhibitors serve as valuable tools, allowing for the investigation of the precise molecular mechanisms governed by C14orf109. The study of this chemical class contributes to a deeper understanding of the role played by C14orf109 in cellular physiology, offering insights into its potential functions within the intricate networks that regulate various cellular processes. Overall, the exploration of C14orf109 inhibitors provides a platform for advancing our understanding of the molecular landscape surrounding this less-explored member of the open reading frame family.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts the Golgi apparatus by blocking protein transport from the endoplasmic reticulum, which could inhibit the trafficking of lysosomal enzymes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, which is critical for the proper folding and function of many lysosomal enzymes, potentially disrupting their trafficking. | ||||||
Swainsonine | 72741-87-8 | sc-201362 sc-201362C sc-201362A sc-201362D sc-201362B | 1 mg 2 mg 5 mg 10 mg 25 mg | $135.00 $246.00 $619.00 $799.00 $1796.00 | 6 | |
Swainsonine inhibits mannosidase II, an enzyme involved in the processing of N-glycans, which could affect the sorting and trafficking of lysosomal enzymes. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is an ionophore that disrupts Golgi function, altering glycosylation and potentially affecting lysosomal enzyme trafficking. | ||||||
Castanospermine | 79831-76-8 | sc-201358 sc-201358A | 100 mg 500 mg | $180.00 $620.00 | 10 | |
Castanospermine is a glucosidase inhibitor that interferes with the trimming of glycoproteins, which may disrupt the recognition and transport of lysosomal enzymes. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin and prevents microtubule polymerization, which can disrupt intracellular transport, including that of lysosomal enzymes. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D disrupts actin filaments, which are necessary for vesicular transport mechanisms, potentially affecting lysosomal enzyme trafficking. | ||||||
Deoxynojirimycin | 19130-96-2 | sc-201369 sc-201369A | 1 mg 5 mg | $72.00 $142.00 | ||
Deoxynojirimycin inhibits glucosidases, which are involved in the glycan processing of lysosomal enzymes, possibly disrupting their normal trafficking. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine raises the pH of lysosomes, which can affect the function and trafficking of lysosomal enzymes by inhibiting their post-translational modification. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization, which is essential for vesicle transport processes, possibly impacting lysosomal enzyme trafficking. | ||||||