C10orf64 Inhibitors
C10orf64 Inhibitors refers to a class of chemical compounds specifically designed to target and inhibit the activity of the C10orf64 protein. C10orf64, also known as chromosome 10 open reading frame 64, is a protein-coding gene located on chromosome 10 in humans. While the precise function of C10orf64 is not yet fully elucidated, research suggests its involvement in various cellular processes, potentially linked to signal transduction pathways and regulatory mechanisms within the cell.
Chemical inhibitors designed for C10orf64 act by selectively binding to the protein and modulating its function. These inhibitors are often meticulously engineered to interact with specific regions of the C10orf64 protein, disrupting its normal activity. The development of C10orf64 inhibitors is rooted in the broader field of targeted molecular interventions, aiming to understand and manipulate cellular functions at the molecular level. By inhibiting C10orf64, researchers seek to unravel the biological consequences of this protein's modulation and gain insights into its role in cellular physiology. The exploration of C10orf64 inhibitors contributes to advancing our understanding of cellular pathways and may open avenues for further research in the realm of molecular biology and cellular signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3K). By inhibiting PI3K, wortmannin can affect downstream signaling pathways such as AKT/PKB signaling, which is critical for cell survival and proliferation. C10orf64, if involved in these pathways, would have its functional activity decreased due to reduced survival signals. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is another PI3K inhibitor, similar to wortmannin. It blocks the PI3K-dependent AKT signaling pathway, leading to decreased survival and proliferation signals, which could indirectly decrease the functional activity of C10orf64 if it is part of this signaling cascade. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that prevents the activation of mTORC1, a downstream target of PI3K/AKT signaling. This inhibition would lead to a decrease in cell growth and protein synthesis signals, potentially affecting C10orf64 activity if it is implicated in mTOR signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a selective inhibitor of MEK1/2, which are upstream activators of the ERK/MAPK signaling pathway. By inhibiting this pathway, PD98059 could suppress cell proliferation and differentiation signals, indirectly affecting C10orf64 if it functions within this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is also an inhibitor of MEK1/2, leading to downregulation of the ERK/MAPK pathway. C10orf64's activity would be affected if it is involved in this signaling cascade, due to decreased mitogenic and survival signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK, which is involved in response to stress signals and cytokines. If C10orf64 is functionally connected to the p38 MAPK pathway, SB203580 would inhibit its activity by blocking this pathway's signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which modulates cellular processes such as apoptosis and inflammation. Inhibition of JNK signaling could alter the function of C10orf64 if it is involved in these stress response pathways. | ||||||
NF 449 | 389142-38-5 | sc-203159 | 10 mg | $314.00 | 5 | |
NF449 is a potent and selective Gs-alpha inhibitor. It blocks G-protein-coupled receptor signaling, which can impact a wide array of cellular functions. If C10orf64 is involved in GPCR pathways, its activity would be decreased by NF449. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $105.00 $299.00 $474.00 | 15 | |
Go 6983 is a pan-protein kinase C (PKC) inhibitor, affecting multiple isoforms of PKC. PKC signaling is involved in various cellular functions, and inhibition by Go 6983 could decrease C10orf64 activity if it is PKC-dependent. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor, leading to altered actin cytoskeleton dynamics and cell motility. If C10orf64 plays a role in pathways involving ROCK, this compound would result in decreased functional activity of C10orf64. | ||||||