BTBD11 Activators

BTBD11 (BTB Domain Containing 11) is a protein that in humans is encoded by the BTBD11 gene. It belongs to a family of proteins characterized by the presence of a BTB (Broad-Complex, Tramtrack, and Bric à brac) domain. The BTB domain is a protein-protein interaction motif, suggesting that BTBD11 may be involved in mediating specific protein-protein interactions.In the context of disease, alterations in BTBD11 have been associated with certain types of cancer. For instance, BTBD11 has been identified as a potential novel oncogene in non-small cell lung cancer, with its overexpression promoting cell proliferation and tumorigenesis.

In terms of molecular function, BTBD11 has been shown in yeast two-hybrid screens to interact with the protein NACC1, a transcriptional repressor involved in cell growth and differentiation. This suggests a potential role for BTBD11 in transcriptional regulation and cellular development.These insights, while intriguing, only scratch the surface of BTBD11's potential roles. Further research is needed to fully elucidate the functional roles of BTBD11 and the implications of its dysregulation in human health and disease.